Human cancer evolution in the context of a human immune system in mice
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DOI: 10.1002/1878-0261.12374
Abstract: Immunotherapy is one of the most promising cancer treatment modalities, but the lack of appropriate preclinical in vivo models hampers the development of novel immunotherapeutic strategies. Here, we studied the ability of transplanted human cancer… read more here.
Keywords: human cancer; system mice; immune system; cancer ... See more keywords
The Utility of Human Immune System Mice for High-Containment Viral Hemorrhagic Fever Research
Sign Up to like & getrecommendations! Published in 2020 at "Vaccines"
DOI: 10.3390/vaccines8010098
Abstract: Human immune system (HIS) mice are a subset of humanized mice that are generated by xenoengraftment of human immune cells or tissues and/or their progenitors into immunodeficient mice. Viral hemorrhagic fevers (VHFs) cause severe disease… read more here.
Keywords: immune; system mice; immune system; human immune ... See more keywords