Targeting the contact system in a rabbit model of extracorporeal membrane oxygenation
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DOI: 10.1182/bloodadvances.2022007586
Abstract: Key Points • Factors XII and XI drive thrombosis in ECMO. FXII appears to promote organ damage in ECMO independent of thrombin generation.• Thrombin-mediated activation of FXI may overshadow the role of FXII in ECMO… read more here.
Keywords: contact system; targeting contact; rabbit model; system rabbit ... See more keywords