Systematic morphological profiling of human gene and allele function via Cell Painting
Sign Up to like & getrecommendations! Published in 2017 at "eLife"
DOI: 10.7554/elife.24060
Abstract: We hypothesized that human genes and disease-associated alleles might be systematically functionally annotated using morphological profiling of cDNA constructs, via a microscopy-based Cell Painting assay. Indeed, 50% of the 220 tested genes yielded detectable morphological… read more here.
Keywords: systematic morphological; cell painting; morphological profiling; function ... See more keywords