Genetic barcoding systematically compares genes in del(5q) MDS and reveals a central role for CSNK1A1 in clonal expansion
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DOI: 10.1182/bloodadvances.2021006061
Abstract: Key Points Csnk1a1 haploinsufficient hematopoietic stem cells outcompete other key genes in del(5q) MDS in direct competitive transplantation. Chronic inflammatory stress increases the competitive advantage of Csnk1a1 haploinsufficient hematopoietic stem cells. read more here.
Keywords: del mds; barcoding systematically; genes del; genetic barcoding ... See more keywords