Systemic Adenosine Triphosphate Impairs Neutrophil Chemotaxis and Host Defense in Sepsis
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DOI: 10.1097/ccm.0000000000002052
Abstract: Objective: Sepsis remains an unresolved clinical problem. Therapeutic strategies focusing on inhibition of neutrophils (polymorphonuclear neutrophils) have failed, which indicates that a more detailed understanding of the underlying pathophysiology of sepsis is required. Polymorphonuclear neutrophil… read more here.
Keywords: sepsis; systemic adenosine; polymorphonuclear neutrophil; adenosine triphosphate ... See more keywords