Quantitative [18F]florbetapir PET/CT may identify lung involvement in patients with systemic AL amyloidosis
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-019-04627-7
Abstract: The clinical diagnosis of pulmonary involvement in individuals with systemic AL amyloidosis remains challenging. [18F]florbetapir imaging has previously identified AL amyloid deposits in the heart and extra-cardiac organs. The aim of this study is to… read more here.
Keywords: 18f florbetapir; amyloidosis; systemic amyloidosis; quantitative 18f ... See more keywords
Echocardiographic and pathologic findings of wild-type transthyretin senile systemic amyloidosis developed in early 50s
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Echocardiography"
DOI: 10.1007/s12574-018-0380-x
Abstract: A 63-year-old male with heart failure was admitted to our hospital. He had past medical history of bilateral carpal tunnel syndrome (CTS) in his early 50s. Cardiomegaly had been detected 6 years ago, and echocardiography… read more here.
Keywords: senile systemic; early 50s; heart failure; amyloidosis ... See more keywords
Renal Involvement in Systemic Amyloidosis Caused by Monoclonal Immunoglobulins.
Sign Up to like & getrecommendations! Published in 2020 at "Hematology/oncology clinics of North America"
DOI: 10.1016/j.hoc.2020.08.002
Abstract: Kidney involvement in immunoglobulin-related amyloidosis (AIg) is common. Although patients with renal-limited AIg tend not to have the high mortality that patients with cardiac amyloidosis have, they do experience significant morbidity and impact on quality… read more here.
Keywords: involvement systemic; amyloidosis caused; caused monoclonal; systemic amyloidosis ... See more keywords
Systemic Amyloidosis Caused by Monoclonal Immunoglobulins: Soft Tissue and Vascular Involvement.
Sign Up to like & getrecommendations! Published in 2020 at "Hematology/oncology clinics of North America"
DOI: 10.1016/j.hoc.2020.08.004
Abstract: Clinical features of soft tissue amyloid light-chain (AL) amyloidosis include macroglossia, arthropathy, muscle pseudohypertrophy, skin plaques, and carpal tunnel syndrome. Vascular manifestations of AL amyloid include periorbital ecchymosis, jaw or limb claudication, and even myocardial… read more here.
Keywords: soft tissue; amyloidosis caused; caused monoclonal; amyloidosis ... See more keywords
A transgenic mouse model reproduces human hereditary systemic amyloidosis.
Sign Up to like & getrecommendations! Published in 2019 at "Kidney international"
DOI: 10.1016/j.kint.2019.03.013
Abstract: Amyloidoses are rare life-threatening diseases caused by protein misfolding of normally soluble proteins. The fatal outcome is predominantly due to renal failure and/or cardiac dysfunction. Because amyloid fibrils formed by all amyloidogenic proteins share structural… read more here.
Keywords: mice; mouse model; hereditary systemic; systemic amyloidosis ... See more keywords
Challenging the myths of cardiac amyloidosis.
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DOI: 10.1093/eurheartj/ehx210
Abstract: The scientific history of systemic amyloidosis is replete with reports of incremental advancements reflecting developments in diagnostic tools and therapies, punctuated by frequent paradigm shifts that challenge the conventional wisdom of the day. First identified… read more here.
Keywords: diagnosis; challenging myths; amyloidosis; systemic amyloidosis ... See more keywords
Myocardial Uptake of 68Ga-Pentixafor in a Patient With Systemic Amyloidosis.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical nuclear medicine"
DOI: 10.1097/rlu.0000000000004406
Abstract: ABSTRACT A 55-year-old man presented with chest tightness and lower-limb edema for 1 year. Laboratory and imaging examinations suggested cardiac amyloidosis. Both 18F-FDG and 68Ga-pentixafor PET/CT showed increased uptake in the myocardium of the left… read more here.
Keywords: 68ga pentixafor; systemic amyloidosis; myocardial uptake; amyloidosis ... See more keywords
Kidney Transplantation in Systemic Amyloidosis
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DOI: 10.1097/tp.0000000000003170
Abstract: The present review discusses current developments and outcomes of renal transplantation in systemic amyloidosis. Amyloidosis can wreak havoc on the architecture and functioning of the kidneys, leading to end-stage renal disease. In recent years, the… read more here.
Keywords: kidney transplantation; transplantation; systemic amyloidosis; transplantation systemic ... See more keywords
Transthyretin amyloid deposits in lumbar spinal stenosis and assessment of signs of systemic amyloidosis
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Internal Medicine"
DOI: 10.1111/joim.13222
Abstract: Wild‐type transthyretin (ATTRwt) amyloidosis is the most common systemic amyloidosis in Western countries and manifests mainly as progressive restrictive cardiomyopathy. read more here.
Keywords: amyloid deposits; amyloidosis; systemic amyloidosis; deposits lumbar ... See more keywords
Systemic light-chain amyloidosis incidentally diagnosed after subtotal parathyroidectomy and thyroid lobectomy
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DOI: 10.1136/bcr-2020-241282
Abstract: A 74-year-old woman with a history of primary hyperparathyroidism, thyroid nodules, atrial fibrillation and pacemaker placement for sick sinus syndrome presented with fatigue, constipation and persistent lower extremity oedema. She underwent subtotal parathyroidectomy and left… read more here.
Keywords: subtotal parathyroidectomy; amyloidosis; systemic amyloidosis; thyroid lobectomy ... See more keywords
Lessons from Four Decades of Systemic Amyloidosis with Renal Involvement
Sign Up to like & getrecommendations! Published in 2022 at "Nephron"
DOI: 10.1159/000525675
Abstract: Background: Apart from ATTR amyloidosis, the epidemiology and outcomes of the most common subtypes of systemic amyloidosis in Portugal remain primarily unknown. Methods: This retrospective cohort study evaluated patients with renal biopsy-proven amyloidosis, diagnosed from… read more here.
Keywords: four decades; presentation; lessons four; systemic amyloidosis ... See more keywords