Articles with "systemic cd4" as a keyword



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Functional systemic CD4 immunity is required for clinical responses to PD‐L1/PD‐1 blockade therapy

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Published in 2019 at "EMBO Molecular Medicine"

DOI: 10.15252/emmm.201910293

Abstract: The majority of lung cancer patients progressing from conventional therapies are refractory to PD‐L1/PD‐1 blockade monotherapy. Here, we show that baseline systemic CD4 immunity is a differential factor for clinical responses. Patients with functional systemic… read more here.

Keywords: functional systemic; cd4 immunity; immunity; systemic cd4 ... See more keywords
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Systemic CD4 immunity: A powerful clinical biomarker for PD‐L1/PD‐1 immunotherapy

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Published in 2020 at "EMBO Molecular Medicine"

DOI: 10.15252/emmm.202012706

Abstract: The search for non‐invasive systemic biomarkers of response to PD‐L1/PD‐1 blockade immunotherapy is currently a priority in oncoimmunology. In contrast to classical tumor biomarkers, the identification of clinically useful immunological biomarkers is certainly a challenge,… read more here.

Keywords: cd4 immunity; immunotherapy; systemic cd4; cell ... See more keywords