Association between oral sildenafil dosing, predicted exposure, and systemic hypotension in hospitalised infants
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DOI: 10.1017/s1047951117001639
Abstract: Abstract Background The relationship between sildenafil dosing, exposure, and systemic hypotension in infants is incompletely understood. Objectives The aim of this study was to characterise the relationship between predicted sildenafil exposure and hypotension in hospitalised… read more here.
Keywords: exposure systemic; exposure; sildenafil; systemic hypotension ... See more keywords
Angiotensin II-Related Activation of Scleral Fibroblasts and Their Role on Retinal Ganglion Cell Death in Glaucoma
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DOI: 10.3390/ph16040556
Abstract: We identify the angiotensin II (AngII)-associated changes in the extracellular matrix (ECM) and the biomechanical properties of the sclera after systemic hypotension. Systemic hypotension was induced by administering oral hydrochlorothiazide. AngII receptor levels and ECM… read more here.
Keywords: hypotension; cell; systemic hypotension; sclera systemic ... See more keywords