Articles with "systemic il13" as a keyword



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Pharmacokinetic-Pharmacodynamic Modelling of Systemic IL13 Blockade by Monoclonal Antibody Therapy: A Free Assay Disguised as Total

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Published in 2021 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics13040519

Abstract: A sequential pharmacokinetic (PK) and pharmacodynamic (PD) model was built with Nonlinear Mixed Effects Modelling based on data from a first-in-human trial of a novel biologic, MEDI7836. MEDI7836 is a human immunoglobulin G1 lambda (IgG1λ-YTE)… read more here.

Keywords: systemic il13; medi7836; target; il13 ... See more keywords