Systemic immune changes accompany combination treatment with immunotoxin LMB‐100 and nab‐paclitaxel
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5290
Abstract: LMB‐100 is a novel immune‐conjugate (immunotoxin) that targets mesothelin. A phase 1/2 clinical trial was conducted (NCT02810418) with primary objectives assessing the safety and efficacy of LMB‐100 ± nab‐paclitaxel. Participant blood samples were analyzed for changes in… read more here.
Keywords: lmb 100; 100 nab; combination; systemic immune ... See more keywords
Systemic immune‐inflammation index as a prognostic marker for advanced chronic heart failure with renal dysfunction
Sign Up to like & getrecommendations! Published in 2022 at "ESC Heart Failure"
DOI: 10.1002/ehf2.14217
Abstract: We aim to investigate the correlation between high levels of the systemic immune‐inflammation index (SII) and long‐term mortality and major cardiovascular adverse events in advanced chronic heart failure patients with renal dysfunction. read more here.
Keywords: heart failure; systemic immune; heart; immune inflammation ... See more keywords
Outcome of extracorporeal photopheresis in mycosis fungoides patients is not predicted by quotients of systemic immune‐inflammatory biomarkers
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Apheresis"
DOI: 10.1002/jca.21982
Abstract: Systemic immune‐inflammatory biomarkers (SIIBs) have not been studied in mycosis fungoides (MF) patients undergoing extracorporeal photopheresis (ECP). read more here.
Keywords: inflammatory biomarkers; systemic immune; immune inflammatory; fungoides patients ... See more keywords
Systemic immune‐inflammation index, neutrophil‐to‐lymphocyte ratio, platelet‐to‐lymphocyte ratio can predict clinical outcomes in patients with metastatic non‐small‐cell lung cancer treated with nivolumab
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.22964
Abstract: Explore markers to predict the clinical outcomes of checkpoint inhibitors have high unmet needs. The following study investigates whether hematologic parameter such as systemic immune‐inflammation index (SII), neutrophil‐to‐lymphocyte ratio (NLR), platelet‐to‐lymphocyte ratio (PLR) is associated… read more here.
Keywords: predict clinical; clinical outcomes; systemic immune; lymphocyte ratio ... See more keywords
The predictive value of a preoperative systemic immune‐inflammation index and prognostic nutritional index in patients with esophageal squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27052
Abstract: Growing evidence indicates that systemic inflammation response and malnutrition status are correlated with survival in certain types of solid tumors. The aim of this study is to evaluate the association between the systemic immune‐inflammation index… read more here.
Keywords: sii; index; immune inflammation; systemic immune ... See more keywords
Prognostic value of pretreatment systemic immune‐inflammation index in patients with gastrointestinal cancers
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27373
Abstract: Numerous studies have reported the relationship between systemic immune‐inflammation index (SII) and prognosis in gastrointestinal (GI) cancers, but no consensus has been reached. We aimed to systematically evaluate the prognostic value of SII in patients… read more here.
Keywords: inflammation index; immune inflammation; prognostic value; systemic immune ... See more keywords
Evaluation of the efficiency of the systemic immune‐inflammation index in differentiating parapneumonic effusion from empyema
Sign Up to like & getrecommendations! Published in 2022 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.25926
Abstract: To evaluate the effectiveness of the systemic immune‐inflammation index (SII) and other biomarkers in distinguishing parapneumonic effusion (PPE) and empyema. read more here.
Keywords: parapneumonic effusion; inflammation index; systemic immune; immune inflammation ... See more keywords
Prognostic role of the systemic immune–inflammation index in upper tract urothelial carcinoma treated with radical nephroureterectomy: results from a large multicenter international collaboration
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-021-02884-w
Abstract: To investigate the prognostic role of the preoperative systemic immune–inflammation index (SII) in patients with upper tract urothelial carcinoma (UTUC) treated with radical nephroureterectomy (RNU). We retrospectively analyzed our multi-institutional database to identify 2492 patients.… read more here.
Keywords: inflammation index; immune inflammation; regression; prognostic role ... See more keywords
Can Systemic Immune-Inflammation Index (SII) be a prognostic factor of Bell’s palsy patients?
Sign Up to like & getrecommendations! Published in 2020 at "Neurological Sciences"
DOI: 10.1007/s10072-020-04921-5
Abstract: Recent studies showed that the neutrophil-to-lymphocyte ratio (NLR) and that platelet-to-lymphocyte ratio (PLR) can be used as inflammatory markers in Bell’s palsy. In this study, the aim is to investigate a novel inflammatory index, the… read more here.
Keywords: index; palsy patients; bell palsy; bell ... See more keywords
Local Necrotic Cells Trigger Systemic Immune Activation via Gut Microbiome Dysbiosis in Drosophila.
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.107938
Abstract: Necrotic cells elicit an inflammatory response through their endogenous factors with damage-associated molecular patterns. Blocking apoptosis in Drosophila wings leads to the necrosis-driven systemic immune response by unknown mechanisms. Here, we demonstrate that immune activation… read more here.
Keywords: immune activation; response; necrotic cells; systemic immune ... See more keywords
Systemic immune-inflammation index predicts prognosis in patients with epithelial ovarian cancer: A retrospective study.
Sign Up to like & getrecommendations! Published in 2019 at "Gynecologic oncology"
DOI: 10.1016/j.ygyno.2018.11.034
Abstract: OBJECTIVE The study aimed to investigate the prognostic value of the systemic immune-inflammation index (SII) in patients with epithelial ovarian cancer (EOC). METHODS A total of 553 EOC patients were retrospectively analyzed. 250 patients from… read more here.
Keywords: patients epithelial; epithelial ovarian; inflammation index; immune inflammation ... See more keywords