Articles with "systemic lipid" as a keyword



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mTORC1 restrains adipocyte lipolysis to prevent systemic hyperlipidemia

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Published in 2020 at "Molecular Metabolism"

DOI: 10.1016/j.molmet.2019.12.003

Abstract: Objective Pharmacological agents targeting the mTOR complexes are used clinically as immunosuppressants and anticancer agents and can extend the lifespan of model organisms. An undesirable side effect of these drugs is hyperlipidemia. Although multiple roles… read more here.

Keywords: fed state; hyperlipidemia; mtorc1; lipolysis ... See more keywords
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TMEM41B, a novel ER phospholipid scramblase mediating systemic lipid metabolism

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Published in 2022 at "Acta Biochimica et Biophysica Sinica"

DOI: 10.3724/abbs.2022168

Abstract: The phospholipid molecules forming the phospholipid bilayer membrane have difficulties to complete spontaneous trans-bilayer shuttling due to the physicochemical properties and biological functions of the membrane bilayer [1]. However, this transbilayer phospholipid transport is essential… read more here.

Keywords: phospholipid scramblase; novel phospholipid; systemic lipid; mediating systemic ... See more keywords