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   Articles with "systemic lupus" as a keyword



Interventions for Cutaneous Disease in Systemic Lupus Erythematosus: Summary of a Cochrane Review.

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recommendations! Published in 2022 at "JAMA dermatology"

DOI: 10.1001/jamadermatol.2021.5485

Abstract: Clinical Question What is the efficacy of interventions for cutaneous disease in systemic lupus erythematosus (SLE) in randomized clinical trials (RCTs)? Bottom Line Available RCT evidence on the management of cutaneous disease in SLE is… read more here.

Keywords: disease; cutaneous disease; systemic lupus; interventions cutaneous ... See more keywords

Vascular-Targeted Therapy for Systemic Lupus Erythematosus-Associated Vasculitis.

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recommendations! Published in 2023 at "JAMA dermatology"

DOI: 10.1001/jamadermatol.2023.0077

Abstract: This case report describes a woman in her 40s with a medical history of systemic lupus erythematosus with 1 year of tender papules, plaques, and progressive ulcers on her hands and feet. read more here.

Keywords: lupus erythematosus; targeted therapy; systemic lupus; vascular targeted ... See more keywords

Mycophenolate Mofetil and New-Onset Systemic Lupus Erythematosus

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recommendations! Published in 2024 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2024.32131

Abstract: Key Points Question What are the efficacy and safety of mycophenolate mofetil (MMF) in patients with new-onset systemic lupus erythematosus (SLE), with high titers of anti–double-stranded DNA antibody, and without major organ involvement? Findings This… read more here.

Keywords: new onset; onset systemic; mycophenolate mofetil; systemic lupus ... See more keywords

Population pharmacokinetic modelling of prednisolone in systemic lupus erythematosus patients: Analysis of exposure and disease activity

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recommendations! Published in 2025 at "British Journal of Clinical Pharmacology"

DOI: 10.1002/bcp.70103

Abstract: Prednisone is a widely used glucocorticoid in the treatment of lupus, although its dosing is often determined empirically. Prednisolone, the active metabolite of prednisone, is found in its free form in the serum. The goal… read more here.

Keywords: population pharmacokinetic; disease activity; lupus erythematosus; systemic lupus ... See more keywords

Identification of Key Biomarkers for Systemic Lupus Erythematosus Progression and Therapy Response: A Bulk RNA‐Sequencing‐Based Bioinformatics Study

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recommendations! Published in 2025 at "Brain and Behavior"

DOI: 10.1002/brb3.71098

Abstract: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects multiple organs and has a higher prevalence in women of reproductive age. The increasing global incidence of this disease poses a significant public health… read more here.

Keywords: key biomarkers; identification key; lupus erythematosus; systemic lupus ... See more keywords

Tolerogenic probiotics Lactobacillus delbrueckii and Lactobacillus rhamnosus promote anti‐inflammatory profile of macrophages‐derived monocytes of newly diagnosed patients with systemic lupus erythematosus

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recommendations! Published in 2024 at "Cell Biochemistry and Function"

DOI: 10.1002/cbf.3981

Abstract: Systemic lupus erythematosus (SLE) is known as an autoimmune disorder that is characterized by the breakdown of self‐tolerance, resulting in disease onset and progression. Macrophages have been implicated as a factor in the development of… read more here.

Keywords: rhamnosus; systemic lupus; lactobacillus delbrueckii; expression ... See more keywords

Dnase1‐deficient mice spontaneously develop a systemic lupus erythematosus‐like disease

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recommendations! Published in 2019 at "European Journal of Immunology"

DOI: 10.1002/eji.201847875

Abstract: Systemic lupus erythematosus (SLE) is an autoimmune disease that has high morbidity and can result in multi‐organ damage. SLE is characterized by dysregulated activation of T‐ and B‐lymphocytes and the production of autoantibodies directed against… read more here.

Keywords: dnase1 deficient; systemic lupus; lupus erythematosus; disease ... See more keywords

Systemic lupus erythematosus patients contain B‐cell receptor repertoires sensitive to immunosuppressive drugs

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recommendations! Published in 2022 at "European Journal of Immunology"

DOI: 10.1002/eji.202149596

Abstract: Immune repertoire (IR) during treatment may be a surrogate biomarker for disease response. Changes of the IR in systemic lupus erythematosus patients in response to immunosuppressive drugs were identified in ten SLE patients. Patients provided… read more here.

Keywords: sensitive group; erythematosus patients; immunosuppressive drugs; group ... See more keywords

Persistently active interferon-γ pathway and expansion of T-bet+ B cells in a subset of patients with childhood-onset systemic lupus erythematosus.

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recommendations! Published in 2023 at "European journal of immunology"

DOI: 10.1002/eji.202250319

Abstract: Systemic lupus erythematosus (SLE) is an autoimmune disease causing significant morbidity and mortality, despite important improvements in its management in the last decades. The objective of this work is to investigate the role of IFN-γ… read more here.

Keywords: lupus erythematosus; ifn; systemic lupus; bet ... See more keywords

Interferon-α regulates abnormally increased expression of RSAD2 in Th17 and Tfh cells in systemic lupus erythematosus patients.

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recommendations! Published in 2023 at "European journal of immunology"

DOI: 10.1002/eji.202350420

Abstract: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that often involves abnormal activation of regulatory interferon genes and regulation of B cells by CD4+ T cells. RSAD2 is a viral suppressor protein regulated by… read more here.

Keywords: tfh cells; th17; expression; systemic lupus ... See more keywords

Circulating levels of endogenous complement inhibitors correlate inversely with complement consumption in systemic lupus erythematosus

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recommendations! Published in 2024 at "European Journal of Immunology"

DOI: 10.1002/eji.202450998

Abstract: Systemic lupus erythematosus (SLE) is marked by excessive complement activation, contributing to tissue damage. Complement activation can be detected in many organs including the skin, kidney, and brain. The involvement of the central nervous system… read more here.

Keywords: complement consumption; systemic lupus; factor; complement ... See more keywords