Systemic Metabolic Alteration Dependent on the Thyroid‐Liver Axis in Early PD
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DOI: 10.1002/ana.26510
Abstract: Parkinson's disease (PD) is a common neurodegenerative disease characterized by initial involvement of the olfactory bulb/amygdala or autonomic nerves followed by nigral degeneration. Although autonomic innervation strictly regulates multiorgan systems, including endocrine functions, circulation, and… read more here.
Keywords: thyroid liver; metabolic alteration; dependent thyroid; systemic metabolic ... See more keywords
Muscle‐derived GDF15 drives diurnal anorexia and systemic metabolic remodeling during mitochondrial stress
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DOI: 10.15252/embr.201948804
Abstract: Mitochondrial dysfunction promotes metabolic stress responses in a cell‐autonomous as well as organismal manner. The wasting hormone growth differentiation factor 15 (GDF15) is recognized as a biomarker of mitochondrial disorders, but its pathophysiological function remains… read more here.
Keywords: systemic metabolic; muscle; muscle derived; mitochondrial stress ... See more keywords
Estimation of Human Cerebral Atrophy Based on Systemic Metabolic Status Using Machine Learning
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2022.869915
Abstract: Background Based on the assumption that systemic metabolic disorders affect cognitive function, we have developed a deep neural network (DNN) model that can estimate cognitive function based on basic blood test data that do not… read more here.
Keywords: age; dnn model; systemic metabolic; cerebral atrophy ... See more keywords