Improved systemic metabolism and adipocyte biology in miR-150 knockout mice
Sign Up to like & getrecommendations! Published in 2018 at "Metabolism: clinical and experimental"
DOI: 10.1016/j.metabol.2017.12.018
Abstract: Introduction: Short non-coding micro-RNAs (miRNAs) are post-transcriptional factors that directly regulate protein expression by degrading or inhibiting target mRNAs; however, the role of miRNAs in obesity and cardiometabolic disease remains unclarified. Based on our earlier… read more here.
Keywords: systemic metabolism; mir 150; biology; mice ... See more keywords
Thermogenic stimulation improves systemic metabolism and healthspan outcomes in aged mice
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5796109
Abstract: Adipose tissue metabolism plays a pivotal role in systemic aging by regulating whole-body energy and glucose metabolism. Emerging evidence links increased thermogenesis in the adipose tissue to longevity and potentially delayed onset of age-related diseases.… read more here.
Keywords: metabolism; thermogenic stimulation; systemic metabolism; healthspan outcomes ... See more keywords
Impact of Metformin on Systemic Metabolism and Survival of Patients With Advanced Pancreatic Neuroendocrine Tumors
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2019.00902
Abstract: Pancreatic neuroendocrine tumors (pNETs) represent a subgroup of neuroendocrine malignancies with specific biological and clinical characteristics, whose incidence has increased in the last four decades. The growth and proliferation of pNET cells is especially dependent… read more here.
Keywords: pancreatic neuroendocrine; impact metformin; systemic metabolism; neuroendocrine tumors ... See more keywords
Impact of Physical Activity and Exercise on the Epigenome in Skeletal Muscle and Effects on Systemic Metabolism
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10010126
Abstract: Exercise and physical activity induces physiological responses in organisms, and adaptations in skeletal muscle, which is beneficial for maintaining health and preventing and/or treating most chronic diseases. These adaptations are mainly instigated by transcriptional responses… read more here.
Keywords: systemic metabolism; skeletal muscle; physical activity; muscle ... See more keywords