Regulation of systemic tissue injury by coagulation inhibitors in B6.MRL/lpr autoimmune mice.
Sign Up to like & getrecommendations! Published in 2018 at "Clinical immunology"
DOI: 10.1016/j.clim.2018.08.010
Abstract: Impaired fibrinolysis and complement activation in Systemic Lupus Erythematosus contributes to disease amplification including increased risk of thrombosis and tissue Ischemia/Reperfusion (IR) injury. Previous work has demonstrated complement is a key regulator of tissue injury.… read more here.
Keywords: coagulation; tissue injury; systemic tissue; tissue ... See more keywords
A MAPS Vaccine Induces Multipronged Systemic and Tissue-Resident Cellular Responses and Protects Mice against Mycobacterium tuberculosis
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DOI: 10.1128/mbio.03611-22
Abstract: Tuberculosis (TB) remains a leading cause of morbidity and mortality worldwide. Here, we evaluate a novel vaccine which induces a broad immune response to Mycobacterium tuberculosis including robust antibody responses and long-lived systemic and tissue-resident… read more here.
Keywords: tuberculosis; tissue resident; mycobacterium; systemic tissue ... See more keywords