Severe cresol poisoning caused by massive dermal exposure
Sign Up to like & getrecommendations! Published in 2022 at "Internal and Emergency Medicine"
DOI: 10.1007/s11739-022-02949-3
Abstract: A 34-year-old man with a history of epilepsy was found after falling into a washing tank, containing 60% cresol and 40% xylene in a plastic factory. He was brought to a local hospital, where he… read more here.
Keywords: dermal exposure; exposure; cresol; systemic toxicity ... See more keywords
Local Anesthetic Systemic Toxicity
Sign Up to like & getrecommendations! Published in 2017 at "AORN Journal"
DOI: 10.1016/j.aorn.2017.08.015
Abstract: Abstract Local anesthetics are commonly used in the perioperative environment to facilitate surgical procedures or to provide postoperative pain management for patients. The use of local anesthetics, however, introduces the risk of complications resulting from… read more here.
Keywords: anesthetic systemic; toxicity; local anesthetics; local anesthetic ... See more keywords
Synthesis and systemic toxicity assessment of quinine-triazole scaffold with antiprotozoal potency.
Sign Up to like & getrecommendations! Published in 2019 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2019.102939
Abstract: A series of hybrid antiprotozoal compounds with quinine-triazolyl scaffold were prepared by copper catalyzed Huisgen 1,3-dipolar cycloaddition via O-mesylation with mesyl chloride followed by azide displacement. The synthesized azide derivative was made to react with… read more here.
Keywords: synthesis systemic; quinine triazole; toxicity; toxicity assessment ... See more keywords
Antitumoral effect and reduced systemic toxicity in mice after intra‐tumoral injection of an in vivo solidifying calcium sulfate formulation with docetaxel
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pharmaceutics and Biopharmaceutics"
DOI: 10.1016/j.ejpb.2017.01.018
Abstract: Background: Docetaxel is a cytostatic agent approved for treatment of non‐small cell lung cancer as well as other cancers. Although docetaxel is an effective cytostatic agent, its effectiveness in clinical practice is associated with a… read more here.
Keywords: calcium sulfate; reduced systemic; formulation; intra tumoral ... See more keywords
Systemic toxicity eliciting metal ion levels from metallic implants and orthopedic devices - A Mini Review.
Sign Up to like & getrecommendations! Published in 2021 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2021.07.004
Abstract: The metal/metal alloy-based implants and prostheses are in use for over a century, and the rejections, revisions, and metal particle-based toxicities were reported concurrently. Complications developed due to metal ions, metal debris, and organo-metallic particles… read more here.
Keywords: metal; systemic toxicity; toxicology; metal ion ... See more keywords
WHEN LIGHTING STRIKES TWICE: LOCAL ANESTHETIC SYSTEMIC TOXICITY AND EPINEPHRINE INDUCED STRESS CARDIOMYOPATHY
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American College of Cardiology"
DOI: 10.1016/s0735-1097(20)33458-6
Abstract: Local anesthetics (LAs) are thought to be free of deleterious effects. However, major events have occurred from LAs after any route of administration. We present a case of local anesthetic systemic toxicity (LAST) resulting in… read more here.
Keywords: anesthetic systemic; local anesthetic; lighting strikes; systemic toxicity ... See more keywords
Effect of Surface Modification on the Pulmonary and Systemic Toxicity of Cellulose Nanofibrils.
Sign Up to like & getrecommendations! Published in 2022 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c00072
Abstract: Cellulose nanofibrils (CNFs) have emerged as sustainable options for a wide range of applications. However, the high aspect ratio and biopersistence of CNFs raise concerns about potential health effects. Here, we evaluated the in vivo… read more here.
Keywords: cellulose nanofibrils; pulmonary systemic; systemic toxicity; effect surface ... See more keywords
Strain and Sex Differences in the Vestibular and Systemic Toxicity of 3,3′-Iminodipropionitrile in Mice
Sign Up to like & getrecommendations! Published in 2017 at "Toxicological Sciences"
DOI: 10.1093/toxsci/kfw238
Abstract: The nitrile 3,3'-iminodipropionitrile (IDPN) causes a loss of hair cells in the vestibular epithelium of the inner ear in several species of both mammals and nonmammals. It is of interest as a model compound in… read more here.
Keywords: sex differences; toxicity; mice; systemic toxicity ... See more keywords
Local Anesthetic Systemic Toxicity: A Narrative Literature Review and Clinical Update on Prevention, Diagnosis, and Management.
Sign Up to like & getrecommendations! Published in 2019 at "Plastic and reconstructive surgery"
DOI: 10.1097/prs.0000000000005989
Abstract: BACKGROUND The objective of this narrative review of local anesthetic systemic toxicity is to provide an update on its prevention, diagnosis, and management. METHODS The authors used a MEDLINE search of human studies, animal studies,… read more here.
Keywords: local anesthetic; anesthetic systemic; management; toxicity ... See more keywords
Assessment of Awareness of Local Anaesthetic Systemic Toxicity (LAST) among Postgraduate Trainees
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Clinical Practice"
DOI: 10.1155/2022/4090444
Abstract: Introduction Although uncommon, local anaesthetic systemic toxicity (LAST) may impose fatal risk to the patients. We investigated the awareness of LAST and knowledge on local anaesthetics among our postgraduate trainees. Materials and Methods A total… read more here.
Keywords: anaesthetic systemic; awareness; postgraduate trainees; systemic toxicity ... See more keywords
Systemic toxicity induced by aggregated layered double hydroxide nanoparticles
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s146414
Abstract: Layered double hydroxide (LDH) nanoparticles are emerging as one of the promising nanomaterials for biomedical applications, but their systemic toxicity in vivo has received little attention. In the present study, the effects of inorganic nanoparticle… read more here.
Keywords: layered double; ldh nanoparticles; toxicity; double hydroxide ... See more keywords