Prognostic analysis of three forms of Ki‐67 in patients with breast cancer with non‐pathological complete response before and after neoadjuvant systemic treatment
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DOI: 10.1002/cam4.5693
Abstract: Patients who do not achieve a pathological complete response (pCR) after neoadjuvant systemic treatment (NST) have a significantly worse prognosis. A reliable predictor of prognosis is required to further subdivide non‐pCR patients. To date, the… read more here.
Keywords: complete response; neoadjuvant systemic; systemic treatment; pathological complete ... See more keywords
Focal white matter microstructural alteration after anthracycline-based systemic treatment in long-term breast cancer survivors: a structural magnetic resonance imaging study.
Sign Up to like & getrecommendations! Published in 2021 at "Brain imaging and behavior"
DOI: 10.1007/s11682-021-00551-3
Abstract: Understanding the neural correlates of cognitive problems in patients with breast cancer (BC) after systemic treatment have been a topic of increasing investigation. The heterogeneity of the systemic treatment regimens may undermine our ability to identify brain… read more here.
Keywords: systemic treatment; brain; group; microstructural alteration ... See more keywords
Systemic Treatment of Soft Tissue Sarcomas in the Geriatric Population
Sign Up to like & getrecommendations! Published in 2022 at "Current Treatment Options in Oncology"
DOI: 10.1007/s11864-022-00972-2
Abstract: As the population ages, there will be an increase in the incidence and prevalence of soft tissue sarcoma (STS) within the geriatric population. As this disease disproportionately affects older adults, the percentage of adults >65… read more here.
Keywords: soft tissue; population; treatment; geriatric population ... See more keywords
Systemic Treatment Options for Advanced-Stage Mycosis Fungoides and Sézary Syndrome
Sign Up to like & getrecommendations! Published in 2018 at "Current Oncology Reports"
DOI: 10.1007/s11912-018-0678-x
Abstract: Purpose of ReviewCutaneous T-cell lymphoma (CTCL) is a rare form of non-Hodgkin lymphoma. Globally, the most common subtypes of CTCL are mycosis fungoides and Sézary syndrome. CTCL can confer significant morbidity and even mortality in… read more here.
Keywords: systemic treatment; fungoides zary; zary syndrome; treatment ... See more keywords
Advanced Pancreatic Neuroendocrine Neoplasms: Which Systemic Treatment Should I Start With?
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DOI: 10.1007/s11912-021-01071-5
Abstract: Pancreatic neuroendocrine neoplasms (panNENs) often present as advanced disease and there is little data to guide treatment sequencing in the advance disease setting. Therefore, we aim to provide a comprehensive summary of the current evidence… read more here.
Keywords: systemic treatment; pancreatic neuroendocrine; treatment; neuroendocrine neoplasms ... See more keywords
Measurement of the Psychological Impact of Psoriasis on Patients Receiving Systemic Treatment.
Sign Up to like & getrecommendations! Published in 2018 at "Actas dermo-sifiliograficas"
DOI: 10.1016/j.ad.2018.05.007
Abstract: BACKGROUND AND OBJECTIVES The negative impact of psoriasis on patient quality of life can be as important as the physical consequences of the disease. We could assume that clearance of the disease would also lead… read more here.
Keywords: systemic treatment; group; impact psoriasis; psoriasis ... See more keywords
Outcome of postmastectomy radiotherapy after primary systemic treatment in patients with clinical T1-2N1 breast cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique"
DOI: 10.1016/j.canrad.2017.07.051
Abstract: PURPOSE The role of postmastectomy radiotherapy following primary systemic treatment in patients with clinical T1-2N1 breast cancer remains a controversial issue. The purpose of this study was to evaluate the benefit of postmastectomy radiotherapy following… read more here.
Keywords: systemic treatment; postmastectomy radiotherapy; radiotherapy; primary systemic ... See more keywords
Novel systemic treatment approaches for metastatic pancreatic cancer
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Investigational Drugs"
DOI: 10.1080/13543784.2022.2037552
Abstract: ABSTRACT Introduction Pancreatic ductal adenocarcinoma (PDAC) has a 5-year overall survival rate of 10%, emphasizing the need for more effective therapies, especially in metastatic disease. The immunosuppressive tumor microenvironment, poor vascularization, and dense tumor stroma… read more here.
Keywords: treatment approaches; metastatic pancreatic; approaches metastatic; systemic treatment ... See more keywords
Current systemic treatment strategies for hidradenitis suppurativa
Sign Up to like & getrecommendations! Published in 2017 at "Expert Opinion on Orphan Drugs"
DOI: 10.1080/21678707.2017.1281735
Abstract: ABSTRACT Introduction: Hidradenitis suppurativa (HS) is a chronic, inflammatory, debilitating disease of a relapsing nature involving nodules, abscesses and suppurating lesions of intertriginous areas of the skin. Within recent years there has been a progress… read more here.
Keywords: systemic treatment; current systemic; treatment; treatment strategies ... See more keywords
Does severe toxicity affect global quality of life in patients with metastatic colorectal cancer during palliative systemic treatment? A systematic review
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DOI: 10.1093/annonc/mdw617
Abstract: Background New palliative systemic treatment regimens in patients with metastatic colorectal cancer (mCRC) have significantly improved overall survival and prognosis. These treatment regimens are often accompanied by increased toxicity, which may impair patients' quality of… read more here.
Keywords: systemic treatment; treatment; toxicity; global qol ... See more keywords
What is the optimal systemic treatment of men with metastatic, hormone-naive prostate cancer? A STOPCAP systematic review and network meta-analysis
Sign Up to like & getrecommendations! Published in 2018 at "Annals of Oncology"
DOI: 10.1093/annonc/mdy071
Abstract: Abstract Background Our prior Systemic Treatment Options for Cancer of the Prostate systematic reviews showed improved survival for men with metastatic hormone-naive prostate cancer when abiraterone acetate plus prednisolone/prednisone (AAP) or docetaxel (Doc), but not… read more here.
Keywords: systemic treatment; network; treatment; metastatic hormone ... See more keywords