Systemic treatments and outcomes in CIC ‐rearranged Sarcoma: A national multi‐centre clinicopathological series and literature review
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.4580
Abstract: CIC‐rearranged sarcoma is a recently established, ultra‐rare, molecularly defined sarcoma subtype. We aimed to further characterise clinical features of CIC‐rearranged sarcomas and explore clinical management including systemic treatments and outcomes. read more here.
Keywords: outcomes cic; systemic treatments; treatments outcomes; rearranged sarcoma ... See more keywords
Systematic evaluation of the efficacy‐effectiveness gap of systemic treatments in extensive disease small cell lung cancer
Sign Up to like & getrecommendations! Published in 2020 at "Pharmacoepidemiology and Drug Safety"
DOI: 10.1002/pds.5179
Abstract: The aim of this study is to assess how clinical outcomes in real‐world (effectiveness) correspond to the outcomes in clinical trials (efficacy) of systemic treatments for extensive disease small cell lung cancer (ED SCLC). read more here.
Keywords: treatments extensive; cell lung; extensive disease; disease small ... See more keywords
[Off-label drugs in childhood psoriasis].
Sign Up to like & getrecommendations! Published in 2020 at "Annales de dermatologie et de venereologie"
DOI: 10.1016/j.annder.2020.01.021
Abstract: INTRODUCTION Psoriasis affects 0.5% of children in Europe, with moderate to severe clinical forms in 15-35% of cases warranting the use of systemic treatments. Few treatments are licensed for childhood psoriasis. In this study, we… read more here.
Keywords: label; childhood psoriasis; treatment; study ... See more keywords
Activity of Systemic Treatments After Cabozantinib Failure in Advanced Metastatic Renal Cell Carcinoma.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical genitourinary cancer"
DOI: 10.1016/j.clgc.2021.09.001
Abstract: BACKGROUND Cabozantinib, a potent multityrosine kinases inhibitor (TKI), has demonstrated overall survival (OS) benefit over everolimus in patients previously treated with VEGFR TKI for metastatic Renal Cell Carcinoma (mRCC). The efficacy of systemic treatments after… read more here.
Keywords: renal cell; cell carcinoma; systemic treatments; cabozantinib failure ... See more keywords
Cardiovascular toxicities of systemic treatments of prostate cancer: is oestrogen to the rescue?
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DOI: 10.1038/nrurol.2017.127
Abstract: Cardiovascular toxicities of systemic treatments of prostate cancer: is oestrogen to the rescue? read more here.
Keywords: toxicities systemic; cardiovascular toxicities; prostate cancer; systemic treatments ... See more keywords
Systemic treatments for metastatic urothelial carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2018.1544242
Abstract: ABSTRACT Introduction: Urothelial carcinoma is one of the most common cancers in the western world and, until recently, had limited therapeutic options. The contemporary advancement of immune checkpoint inhibitors (ICI) has heralded a new era… read more here.
Keywords: carcinoma; treatment; systemic treatments; urothelial carcinoma ... See more keywords
Systemic Treatments for Allergic Contact Dermatitis.
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DOI: 10.1097/der.0000000000000435
Abstract: Allergic contact dermatitis is a common disease within the family of delayed-type hypersensitivity reactions. In more severe cases of allergic contact dermatitis, topical steroids may prove insufficient, and systemic therapeutic agents are often used. Even… read more here.
Keywords: allergic contact; dermatitis systemic; systemic treatments; contact dermatitis ... See more keywords
Systemic treatments for melasma: adjuvant therapy with a novel topical agent
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Dermatology"
DOI: 10.1111/ijd.13887
Abstract: References 1 Durdu M, Guran M, Ilkit M. Epidemiological characteristics of Malassezia folliculitis and use of the May-Grunwald-Giemsa stain to diagnose the infection. Diagn Microbiol Infect Dis 2013; 76: 450–457. 2 Lim SL, Lim CS.… read more here.
Keywords: melasma adjuvant; adjuvant therapy; treatments melasma; systemic treatments ... See more keywords
Efficacy and safety of systemic treatments in psoriatic arthritis: a systematic review, meta‐analysis and GRADE evaluation
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the European Academy of Dermatology and Venereology"
DOI: 10.1111/jdv.15482
Abstract: Twenty per cent of patients with plaque psoriasis also have psoriatic arthritis – a disease affecting joints and entheses. Different treatment options exist but currently no succinct systematic overview exists. A systematic review of approved… read more here.
Keywords: psoriatic arthritis; quality; treatment; systematic review ... See more keywords
Stereotactic ablative radiotherapy and systemic treatments for extracerebral oligometastases, oligorecurrence, oligopersistence and oligoprogression from lung cancer
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DOI: 10.1186/s12885-019-6449-8
Abstract: Background Stereotactic irradiation (SBRT) is a standard of care for inoperable stage I lung cancer and brain oligometastases from lung cancer but is controversial for extracranial oligometastases. We assessed outcomes of lung cancer patients with… read more here.
Keywords: oligometastatic spectrum; oligometastases oligorecurrence; systemic treatments; lung cancer ... See more keywords
Micro-RNAs Predict Response to Systemic Treatments in Metastatic Renal Cell Carcinoma Patients: Results from a Systematic Review of the Literature
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10061287
Abstract: Locally advanced or metastatic renal cell carcinomas (mRCCs) account for up to 15% of all kidney cancer diagnoses. Systemic therapies (with or without surgery) represent gold standard treatments, mostly based on tyrosine kinase inhibitors in… read more here.
Keywords: renal cell; metastatic renal; systemic treatments; systematic review ... See more keywords