Systems metabolic engineering of Streptomyces venezuelae for the enhanced production of pikromycin
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28114
Abstract: Pikromycin is an important precursor of drugs, for example, erythromycin. Hence, systems metabolic engineering for the enhanced pikromycin production can contribute to the development of pikromycinârelated drugs. In this study, metabolic genes in Streptomyces venezuelae… read more here.
Keywords: metabolic engineering; systems metabolic; pikromycin; production ... See more keywords
Systems Metabolic Engineering of Methanotrophic Bacteria for Biological Conversion of Methane to Value-Added Compounds.
Sign Up to like & getrecommendations! Published in 2022 at "Advances in biochemical engineering/biotechnology"
DOI: 10.1007/10_2021_184
Abstract: Methane is considered the carbon source with the highest potential in industrial biotechnology because of its abundance and sustainability. The biological conversion of methane into chemicals or fuels can not only reduce greenhouse gas emissions,… read more here.
Keywords: conversion methane; systems metabolic; engineering; methane ... See more keywords
Towards systems metabolic engineering in Pichia pastoris.
Sign Up to like & getrecommendations! Published in 2017 at "Biotechnology advances"
DOI: 10.1016/j.biotechadv.2017.07.009
Abstract: The methylotrophic yeast Pichia pastoris is firmly established as a host for the production of recombinant proteins, frequently outperforming other heterologous hosts. Already, a sizeable amount of systems biology knowledge has been acquired for this… read more here.
Keywords: engineering; systems metabolic; pastoris; metabolic engineering ... See more keywords
Recent advances in systems metabolic engineering tools and strategies.
Sign Up to like & getrecommendations! Published in 2017 at "Current opinion in biotechnology"
DOI: 10.1016/j.copbio.2017.06.007
Abstract: Metabolic engineering has been playing increasingly important roles in developing microbial cell factories for the production of various chemicals and materials to achieve sustainable chemical industry. Nowadays, many tools and strategies are available for performing… read more here.
Keywords: engineering; systems metabolic; metabolic engineering; biology ... See more keywords
Systems Metabolic Engineering for Efficient Violaxanthin Production in Yeast.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.4c01240
Abstract: Violaxanthin is a plant-derived orange xanthophyll with remarkable antioxidant activity that has wide applications in various industries, such as food, agriculture, and cosmetics. In addition, it is the key precursor of important substances such as… read more here.
Keywords: systems metabolic; efficient; metabolic engineering; violaxanthin production ... See more keywords
Systems Metabolic Engineering of Escherichia coli Coculture for De Novo Production of Genistein.
Sign Up to like & getrecommendations! Published in 2022 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.1c00590
Abstract: Genistein is a plant-derived isoflavone possessing various bioactivities to prevent aging, carcinogenesis, and neurodegenerative and inflammation diseases. As a typical complex flavonoid, its microbial production from sugar remains to be completed. Here, we use systems… read more here.
Keywords: metabolic engineering; systems metabolic; escherichia coli; production ... See more keywords
Comprehensive evaluation of the capacities of microbial cell factories
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-58227-1
Abstract: Systems metabolic engineering is facilitating the development of high-performing microbial cell factories for producing chemicals and materials. However, constructing an efficient microbial cell factory still requires exploring and selecting various host strains, as well as… read more here.
Keywords: systems metabolic; cell factories; engineering; metabolic engineering ... See more keywords
Recent advances in the Design-Build-Test-Learn (DBTL) cycle for systems metabolic engineering of Corynebacterium glutamicum.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of microbiology"
DOI: 10.71150/jm.2501021
Abstract: Existing microbial engineering strategies-encompassing metabolic engineering, systems biology, and systems metabolic engineering-have significantly enhanced the potential of microbial cell factories as sustainable alternatives to the petrochemical industry by optimizing metabolic pathways. Recently, systems metabolic engineering,… read more here.
Keywords: systems metabolic; engineering; biology; metabolic engineering ... See more keywords