In old BALB/c mice, bone marrow pre-B cell and surrogate light chain reduction is associated with increased B cell reactivity to phosphorylcholine, but reduced T15 idiotype dominance
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DOI: 10.1016/j.mad.2016.11.004
Abstract: In young adult BALB/c mice, antibodies to phosphorylcholine (PC) bearing the T15 (TEPC 15) idiotype confer protection against pneumococcal infections. In old age, even though PC reactive B cells are often increased, the proportion of… read more here.
Keywords: t15 idiotype; pre; pre cell; reactivity ... See more keywords