Differential metabolic requirement governed by transcription factor c-Maf dictates innate γδT17 effector functionality in mice and humans
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abm9120
Abstract: Cellular metabolism has been proposed to govern distinct γδ T cell effector functions, but the underlying molecular mechanisms remain unclear. We show that interleukin-17 (IL-17)–producing γδ T (γδT17) and interferon-γ (IFN-γ)–producing γδ T (γδT1) cells… read more here.
Keywords: differential metabolic; t17 effector; maf; transcription factor ... See more keywords