Novel dominant and recessive variants in human ROBO1 cause distinct neurodevelopmental defects through different mechanisms.
Sign Up to like & getrecommendations! Published in 2022 at "Human molecular genetics"
DOI: 10.1093/hmg/ddac070
Abstract: The Roundabout (Robo) receptors, located on growth cones of neurons, induce axon repulsion in response to the extracellular ligand Slit. The Robo family of proteins controls midline crossing of commissural neurons during development in flies.… read more here.
Keywords: human robo1; robo1; t2a gal4; variants human ... See more keywords
Neurotransmitter and Receptor Mapping in Drosophila Circadian Clock Neurons via T2A-GAL4 Screening
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Biological Rhythms"
DOI: 10.1177/07487304251349887
Abstract: The circadian neuronal network in the brain comprises central pacemaker neurons and associated input and output pathways. These components work together to generate coherent rhythmicity, synchronize with environmental time cues, and convey circadian information to… read more here.
Keywords: receptor; receptor genes; neurotransmitter receptor; t2a gal4 ... See more keywords