Identification of novel non-synonymous variants associated with type 2 diabetes-related metabolites in Korean population
Sign Up to like & getrecommendations! Published in 2019 at "Bioscience Reports"
DOI: 10.1042/bsr20190078
Abstract: Abstract Metabolome-genome wide association studies (mGWASs) are useful for understanding the genetic regulation of metabolites in complex diseases, including type 2 diabetes (T2D). Numerous genetic variants associated with T2D-related metabolites have been identified in previous… read more here.
Keywords: variants associated; type diabetes; synonymous variants; related metabolites ... See more keywords
MON-186 An Evaluation of the Ability of Current Exome Sequence Datasets to Retrospectively Validate Drugs for T2D or Related Metabolic Traits
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the Endocrine Society"
DOI: 10.1210/js.2019-mon-186
Abstract: Abstract Human genetics offers the potential to inform on the viability of therapeutic targets through the identification of associations between naturally occurring genetic variants and clinical outcomes. Whole Exome Sequencing (WES) enables comprehensive analysis of… read more here.
Keywords: related metabolic; drug; level; gene ... See more keywords