Protective effects of losartan on some type 2 diabetes mellitus-induced complications in Wistar and spontaneously hypertensive rats
Sign Up to like & getrecommendations! Published in 2020 at "Metabolic Brain Disease"
DOI: 10.1007/s11011-020-00534-1
Abstract: Diabetes mellitus type 2 (T2DM) is characterized by resistance of insulin receptors and/or inadequate insulin secretion resulting in metabolic and structural complications including vascular diseases, arterial hypertension and different behavioral alterations. We aimed to study… read more here.
Keywords: t2dm; spontaneously hypertensive; hypertensive rats; t2dm induced ... See more keywords
Xanthohumol alleviated T2DM-induced liver steatosis and fibrosis by mediating the NRF2/RAGE/NF-κB signaling pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Future medicinal chemistry"
DOI: 10.4155/fmc-2021-0241
Abstract: Hyperglycemia-associated advanced glycation end products (AGEs) and the receptor for AGE (RAGE) contribute to nonalcoholic fatty liver disease (NAFLD). Xanthohumol (XH) exhibits protective activities against liver diseases. Aim: To investigate the effects of XH on Type II diabetes mellitus (T2DM)-induced… read more here.
Keywords: liver steatosis; steatosis fibrosis; t2dm induced; induced liver ... See more keywords