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   Articles with "t2dm rats" as a keyword



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Erratum to: The effect of sinomenine in diabetic neuropathic pain mediated by the P2X3 receptor in dorsal root ganglia

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recommendations! Published in 2017 at "Purinergic Signalling"

DOI: 10.1007/s11302-017-9560-9

Abstract: Type 2 diabetes mellitus (T2DM) accounts for more than 90% of all cases of diabetes mellitus (DM). Diabetic neuropathic pain (DNP) is a common complication of T2DM. Sinomenine is a natural bioactive component extracted from… read more here.

Keywords: t2dm; sinomenine; diabetic neuropathic; p2x3 receptor ... See more keywords
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Terpenoid‐rich Elettaria cardamomum extract prevents Alzheimer‐like alterations induced in diabetic rats via inhibition of GSK3&bgr; activity, oxidative stress and pro‐inflammatory cytokines

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recommendations! Published in 2019 at "Cytokine"

DOI: 10.1016/j.cyto.2018.10.017

Abstract: Purpose: Recent studies suggested that the non‐familiar form of Alzheimer's disease (AD) could be consequence of metabolic syndrome and neuroinflammation. Elettaria cardamomum extract (EC) has exhibited antidiabetic, antioxidant and anti‐inflammatory properties. This research was conducted… read more here.

Keywords: t2dm rats; bgr; elettaria cardamomum; cardamomum extract ... See more keywords
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Gymnemic Acid Ameliorate Hyperglycemia Through PI3K/AKT and AMPK Mediated Signaling Pathway in T2DM Rats.

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recommendations! Published in 2019 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.9b04931

Abstract: Gymnemic acid (GA) isolated from gymnema sylvestre (Retz.) Schult has been shown to display anti-diabetic activity, however the molecular mechanisms governing these effects are unclear. In this study, GA (40, 80 mg/kg/day) was evaluated by… read more here.

Keywords: gymnemic acid; akt ampk; pi3k akt; ampk mediated ... See more keywords
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Dolichandrone serrulata flower improves seminal biochemical parameters and proteins in T2DM rats induced by a high-fat diet and streptozotocin

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recommendations! Published in 2022 at "Pharmaceutical Biology"

DOI: 10.1080/13880209.2022.2124279

Abstract: Abstract Context Although Dolichandrone serrulata (Wall. ex DC.) Seem (Bignoniaceae) flower (DSF) improves hyperglycaemia, testicular damage and sperm quality in type 2 diabetes mellitus (T2DM) animals, its effects on the seminal vesicles, secreting seminal plasma,… read more here.

Keywords: high fat; t2dm rats; t2dm; dolichandrone serrulata ... See more keywords
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Preliminary Study of the Distinctive Mechanism of Shenqi Compound in Treating Rats with Type 2 Diabetes Mellitus by Comparing with Metformin.

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recommendations! Published in 2023 at "Current vascular pharmacology"

DOI: 10.2174/1570161121666230208130349

Abstract: BACKGROUND In China, traditional Chinese medicine (TCM) has been used to treat type 2 diabetes mellitus (T2DM) for centuries. METHODS To investigate how the TCM ShenQi (SQC) formulation differs from metformin, four rat groups, including… read more here.

Keywords: shenqi; pharmacology; t2dm rats; type diabetes ... See more keywords
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Huang-Lian-Jie-Du-Decoction Ameliorates Hyperglycemia and Insulin Resistant in Association With Gut Microbiota Modulation

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recommendations! Published in 2018 at "Frontiers in Microbiology"

DOI: 10.3389/fmicb.2018.02380

Abstract: Background: Huang-Lian-Jie-Du-Decoction (HLJDD), a prescription of traditional Chinese medicine, has been clinically used to treat diabetes for thousands of years and its mechanism was reported to be related to gut microbiota. However, no study has… read more here.

Keywords: t2dm rats; gut; gut microbiota; hljdd treatment ... See more keywords
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Bear bile powder ameliorates type 2 diabetes via modulation of metabolic profiles, gut microbiota, and metabolites

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recommendations! Published in 2023 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2022.1090955

Abstract: Introduction: Bear bile powder (BBP) is widely used in the clinic and has a hypoglycemic effect, but its mechanism is not clear. Methods: In this study, type 2 diabetes mellitus (T2DM) rats induced by a… read more here.

Keywords: bear bile; bbp; type diabetes; bile powder ... See more keywords