A prospective case control study of resistance to rifampicin, dapsone and ofloxacin in Type 1 and Type 2 leprosy reactions and the therapeutic impact of modified treatment regimen on reactions
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the European Academy of Dermatology and Venereology"
DOI: 10.1111/jdv.18709
Abstract: Dear Editor, The clinical manifestations of leprosy are varied and depend on genetic predisposition, environmental and immunological factors and the disease is punctuated by reactional episodes that result in significant morbidity, deformity and disability. AMR… read more here.
Keywords: t2r; reaction; control; resistance ... See more keywords
Neutrophil extracellular traps contribute to the pathogenesis of leprosy type 2 reactions
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DOI: 10.1371/journal.pntd.0007368
Abstract: Up to 50% of patients with the multibacillary form of leprosy are expected to develop acute systemic inflammatory episodes known as type 2 reactions (T2R), thus aggravating their clinical status. Thalidomide rapidly improves T2R symptoms.… read more here.
Keywords: neutrophil extracellular; dna; t2r; pathogenesis ... See more keywords
Mycobacterium leprae and host immune transcriptomic signatures for reactional states in leprosy
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DOI: 10.3389/fmicb.2023.1113318
Abstract: Background Mycobacterium leprae transcriptomic and human host immune gene expression signatures that demonstrate a plausible association with type I (T1R) and type II reactions (T2R) aid in early diagnosis, prevention of nerve damage and consequent… read more here.
Keywords: t2r; reactional states; states leprosy; host ... See more keywords