Novel pyrimidin-4-one derivatives as potential T3SS inhibitors against Xanthomonas campestris pv. campestris.
Sign Up to like & getrecommendations! Published in 2023 at "Pest management science"
DOI: 10.1002/ps.7545
Abstract: BACKGROUND Cruciferous black rot is caused by Xanthomonas campestris pv. campestris (Xcc) infection and is a widespread disease worldwide. Excessive and repeated use of bactericide is an important cause of the development of bacterial resistance.… read more here.
Keywords: t3ss inhibitors; campestris campestris; novel; xanthomonas campestris ... See more keywords
LITESEC-T3SS - Light-controlled protein delivery into eukaryotic cells with high spatial and temporal resolution
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DOI: 10.1038/s41467-020-16169-w
Abstract: Many bacteria employ a type III secretion system (T3SS) injectisome to translocate proteins into eukaryotic host cells. Although the T3SS can efficiently export heterologous cargo proteins, a lack of target cell specificity currently limits its… read more here.
Keywords: t3ss; litesec t3ss; spatial temporal; eukaryotic cells ... See more keywords
Usurping bacterial virulence factors as self-delivery vehicles for therapeutic use
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DOI: 10.1080/21505594.2017.1336595
Abstract: Type III secretion systems (T3SS) as virulence factors were initially discovered in Yersinia and are now widely recognized in many bacterial pathogens that infect animals and plants. It was observed about 20 y ago that… read more here.
Keywords: t3ss; virulence; delivery; virulence factors ... See more keywords
BopN is a Gatekeeper of the Bordetella Type III Secretion System
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DOI: 10.1128/spectrum.04112-22
Abstract: The T3SS is utilized by many Gram-negative bacteria to deliver effector proteins from bacterial cytosol directly into infected host cell cytoplasm in a regulated and targeted manner. Pathogenic bordetellae use the T3SS to inject the… read more here.
Keywords: bordetella; btea; secretion; host ... See more keywords
Ancient co-option of an amino acid ABC transporter locus in Pseudomonas syringae for host signal-dependent virulence gene regulation
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DOI: 10.1371/journal.ppat.1008680
Abstract: Pathogenic bacteria frequently acquire virulence traits via horizontal gene transfer, yet additional evolutionary innovations may be necessary to integrate newly acquired genes into existing regulatory pathways. The plant bacterial pathogen Pseudomonas syringae relies on a… read more here.
Keywords: t3ss; amino acid; virulence; pseudomonas syringae ... See more keywords
A ParDE toxin–antitoxin system is responsible for the maintenance of the Yersinia virulence plasmid but not for type III secretion-associated growth inhibition
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2023.1166077
Abstract: Many Gram-negative pathogens utilize the type III secretion system (T3SS) to translocate virulence-promoting effector proteins into eukaryotic host cells. The activity of this system results in a severe reduction of bacterial growth and division, summarized… read more here.
Keywords: system; growth; virulence plasmid; virulence ... See more keywords
Type 3 Secretion System (T3SS) of Bradyrhizobium sp. DOA9 and Its Roles in Legume Symbiosis and Rice Endophytic Association
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DOI: 10.3389/fmicb.2017.01810
Abstract: The Bradyrhizobium sp. DOA9 strain isolated from a paddy field has the ability to nodulate a wide spectrum of legumes. Unlike other bradyrhizobia, this strain has a symbiotic plasmid harboring nod, nif, and type 3… read more here.
Keywords: t3ss; rice; doa9; bradyrhizobium doa9 ... See more keywords
Molecular Targets and Strategies for Inhibition of the Bacterial Type III Secretion System (T3SS); Inhibitors Directly Binding to T3SS Components
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DOI: 10.3390/biom11020316
Abstract: The type III secretion system (T3SS) is a virulence apparatus used by many Gram-negative pathogenic bacteria to cause infections. Pathogens utilizing a T3SS are responsible for millions of infections yearly. Since many T3SS knockout strains… read more here.
Keywords: t3ss; secretion system; iii secretion; system t3ss ... See more keywords