Two-step target recognition for the competitive inhibition activity of an anti-VEGF aptamer.
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DOI: 10.1261/rna.080524.125
Abstract: The anti-vascular endothelial growth factor (VEGF) aptamer, t44.27, is a 27-mer RNA that functions as the active component of pegaptanib, an anti-angiogenic medicine for neovascular age-related macular degeneration. The t44.27 aptamer is extensively 2'-modified and… read more here.
Keywords: aptamer; competitive inhibition; vegf aptamer; t44 ... See more keywords
Transcriptome and Targeted Hormone Metabolome Reveal the Mechanism of Flower Abscission in Soybeans Under Shade
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DOI: 10.3390/ijms262110303
Abstract: Shade-induced flower abscission in soybean plants is a significant factor limiting yield improvement. Under shaded conditions, significant differences exist in the flower abscission rates among different soybean varieties, but the regulatory mechanisms remain unclear. This… read more here.
Keywords: flower abscission; iaa amino; significantly higher; t44 ... See more keywords