Articles with "t4p" as a keyword



Type IV pili: dynamics, biophysics and functional consequences

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Published in 2019 at "Nature Reviews Microbiology"

DOI: 10.1038/s41579-019-0195-4

Abstract: The surfaces of many bacteria are decorated with long, exquisitely thin appendages called type IV pili (T4P), dynamic filaments that are rapidly polymerized and depolymerized from a pool of pilin subunits. Cycles of pilus extension,… read more here.

Keywords: functional consequences; type pili; t4p dynamics; t4p ... See more keywords

Attenuation of Type IV pili activity by natural products

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Published in 2024 at "Journal of Biomolecular Structure and Dynamics"

DOI: 10.1080/07391102.2024.2310781

Abstract: Abstract The virulence factor Type IV pili (T4P) are surface appendages used by the opportunistic pathogen Pseudomonas aeruginosa for twitching motility and adhesion in the environment and during infection. Additionally, the use of these appendages… read more here.

Keywords: type pili; natural products; t4p; activity ... See more keywords
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Versatile cell surface structures of archaea

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Published in 2018 at "Molecular Microbiology"

DOI: 10.1111/mmi.13889

Abstract: Archaea are ubiquitously present in nature and colonize environments with broadly varying growth conditions. Several surface appendages support their colonization of new habitats. A hallmark of archaea seems to be the high abundance of type… read more here.

Keywords: structures archaea; versatile cell; surface; surface structures ... See more keywords

Removal of Pseudomonas type IV pili by a small RNA virus

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Published in 2024 at "Science"

DOI: 10.1126/science.adl0635

Abstract: The retractile type IV pilus (T4P) is important for virulence of the opportunistic human pathogen Pseudomonas aeruginosa. The single-stranded RNA (ssRNA) phage PP7 binds to T4P and is brought to the cell surface through pilus… read more here.

Keywords: phage; mat; pp7; t4p ... See more keywords

Role of Cyclic Di-GMP and Exopolysaccharide in Type IV Pilus Dynamics

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Published in 2017 at "Journal of Bacteriology"

DOI: 10.1128/jb.00859-16

Abstract: ABSTRACT For Pseudomonas aeruginosa, levels of cyclic di-GMP (c-di-GMP) govern the transition from the planktonic state to biofilm formation. Type IV pili (T4P) are crucial determinants of biofilm structure and dynamics, but it is unknown… read more here.

Keywords: gmp; surface; biofilm formation; cyclic gmp ... See more keywords

Gram-Positive Type IV Pili and Competence.

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Published in 2019 at "Microbiology spectrum"

DOI: 10.1128/microbiolspec.psib-0011-2018

Abstract: Type IV pili (T4P) are remarkable bacterial surface appendages that carry out a range of functions. Various types of T4P have been identified in bacteria and archaea, making them almost universal structures in prokaryotes. T4P… read more here.

Keywords: t4p; gram positive; gram; type pili ... See more keywords

Surface hydrophilicity promotes bacterial twitching motility

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Published in 2024 at "mSphere"

DOI: 10.1128/msphere.00390-24

Abstract: ABSTRACT Twitching motility is a form of bacterial surface translocation powered by the type IV pilus (T4P). It is frequently analyzed by interstitial colony expansion between agar and the polystyrene surfaces of petri dishes. In… read more here.

Keywords: twitching motility; bacterial twitching; t4p; surface ... See more keywords

Interaction of the cyclic-di-GMP binding protein FimX and the Type 4 pilus assembly ATPase promotes pilus assembly

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Published in 2017 at "PLoS Pathogens"

DOI: 10.1371/journal.ppat.1006594

Abstract: Type IVa pili (T4P) are bacterial surface structures that enable motility, adhesion, biofilm formation and virulence. T4P are assembled by nanomachines that span the bacterial cell envelope. Cycles of T4P assembly and retraction, powered by… read more here.

Keywords: pilus assembly; gmp; pilb; t4p ... See more keywords

External Stresses Affect Gonococcal Type 4 Pilus Dynamics

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Published in 2022 at "Frontiers in Microbiology"

DOI: 10.3389/fmicb.2022.839711

Abstract: Bacterial type 4 pili (T4P) are extracellular polymers that serve both as adhesins and molecular motors. Functionally, they are involved in adhesion, colony formation, twitching motility, and horizontal gene transfer. T4P of the human pathogen… read more here.

Keywords: external stresses; hydrogen peroxide; type; pilus ... See more keywords