The CARD8 T60 variant associates with NLRP1 and negatively regulates its activation
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DOI: 10.3389/fimmu.2022.1047922
Abstract: The NLRP1 inflammasome functions as canonical cytosolic sensor in response to intracellular infections and is implicated in auto-inflammatory diseases. But the regulation and signal transduction mechanisms of NLRP1 are incompletely understood. Here, we show that… read more here.
Keywords: card8; t60 variant; nlrp1 inflammasome; negatively regulates ... See more keywords