Commonality and diversity in tRNA substrate recognition in t6A biogenesis by eukaryotic KEOPSs
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DOI: 10.1093/nar/gkac056
Abstract: Abstract N 6-Threonylcarbamoyladenosine (t6A) is a universal and pivotal tRNA modification. KEOPS in eukaryotes participates in its biogenesis, whose mutations are connected with Galloway-Mowat syndrome. However, the tRNA substrate selection mechanism by KEOPS and t6A… read more here.
Keywords: trna substrate; t6a biogenesis; trna; t6a ... See more keywords