Burkholderia cenocepacia utilizes a type VI secretion system for bacterial competition
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DOI: 10.1002/mbo3.774
Abstract: Burkholderia cenocepacia is an opportunistic bacterial pathogen that poses a significant threat to individuals with cystic fibrosis by provoking a strong inflammatory response within the lung. It possesses a type VI secretion system (T6SS), a… read more here.
Keywords: cenocepacia; system; burkholderia cenocepacia; t6ss ... See more keywords
Hcp2b of T6SS affects colonization of avian pathogenic Escherichia coli and host keratin filament expression
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DOI: 10.1080/03079457.2022.2031881
Abstract: ABSTRACT T6SS (type VI secretion system) is a type of nano-syringe that exists in APEC (avian pathogenic Escherichia coli). Hcp (haemolysin-coregulated protein) of T6SS participates in the regulation of virulence during APEC infection. However, whether… read more here.
Keywords: colonization; avian pathogenic; hcp2b; expression ... See more keywords
RpoN/Sfa2-dependent activation of the Pseudomonas aeruginosa H2-T6SS and its cognate arsenal of antibacterial toxins
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DOI: 10.1093/nar/gkab1254
Abstract: Abstract Pseudomonas aeruginosa uses three type six secretion systems (H1-, H2- and H3-T6SS) to manipulate its environment, subvert host cells and for microbial competition. These T6SS machines are loaded with a variety of effectors/toxins, many… read more here.
Keywords: dependent activation; t6ss; pseudomonas aeruginosa; rpon sfa2 ... See more keywords
In silico investigation of the genus Campylobacter type VI secretion system reveals genetic diversity in organization and putative effectors
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DOI: 10.1099/mgen.0.000898
Abstract: Bacterial type VI secretion systems (T6SSs) are contractile nanomachines that deliver proteinic substrates into target prokaryotic or eukaryotic cells and the surrounding milieu. The genus Campylobacter encompasses 39 recognized species and 13 subspecies, with many… read more here.
Keywords: t6ss; type secretion; genus campylobacter; campylobacter ... See more keywords
Sporadic type VI secretion in seventh pandemic Vibrio cholerae.
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DOI: 10.1099/mic.0.001329
Abstract: Vibrio cholerae is a pathogen that causes disease in millions of people every year by colonizing the small intestine and then secreting the potent cholera toxin. How the pathogen overcomes the colonization barrier created by… read more here.
Keywords: cholerae; vibrio cholerae; activity; type secretion ... See more keywords
The AraC‐type transcription factor TagK is a new player in the signaling cascade that induces the anti‐eukaryotic T6SS of Xanthomonas citri
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Microbiology"
DOI: 10.1111/mmi.14985
Abstract: Type 6 secretion systems (T6SSs) are specialized multiprotein complexes that inject protein effectors into prokaryotic and/or eukaryotic cells. We previously described the role of the T6SS of the phytopathogen Xanthomonas citri pv. citri as an… read more here.
Keywords: transcription; factor; citri; anti eukaryotic ... See more keywords
The accessory protein TagV is required for full Type VI secretion system activity in Serratia marcescens
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DOI: 10.1111/mmi.15027
Abstract: The bacterial Type VI secretion system (T6SS) is a dynamic macromolecular structure that promotes inter‐ and intra‐species competition through the delivery of toxic effector proteins into neighbouring cells. The T6SS contains 14 well‐characterised core proteins… read more here.
Keywords: serratia marcescens; tagv; secretion system; activity ... See more keywords
Soil Inoculation and Blocker-Mediated Sequencing Show Effects of the Antibacterial T6SS on Agrobacterial Tumorigenesis and Gallobiome
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DOI: 10.1128/mbio.00177-23
Abstract: The T6SS is widespread among proteobacteria and used for interbacterial competition by agrobacteria, which are soil inhabitants and opportunistic bacterial pathogens causing crown gall disease in a wide range of plants. Current evidence indicates that… read more here.
Keywords: disease; inoculation; competition; soil inoculation ... See more keywords
Atomic Structure of IglD Demonstrates Its Role as a Component of the Baseplate Complex of the Francisella Type VI Secretion System
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DOI: 10.1128/mbio.01277-22
Abstract: Francisella tularensis is a facultatively intracellular Gram-negative bacterium that causes the serious and potentially fatal zoonotic illness, tularemia. Because of its extraordinarily high infectivity and mortality to humans, especially when inhaled, F. tularensis is considered… read more here.
Keywords: francisella; structure; igld; baseplate ... See more keywords
Multiple T6SSs, Mobile Auxiliary Modules, and Effectors Revealed in a Systematic Analysis of the Vibrio parahaemolyticus Pan-Genome
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DOI: 10.1128/msystems.00723-22
Abstract: Gram-negative bacteria employ toxin delivery systems to mediate their interactions with neighboring cells. Vibrio parahaemolyticus, an emerging pathogen of humans and marine animals, was shown to deploy antibacterial toxins into competing bacteria via the type… read more here.
Keywords: pan genome; parahaemolyticus; vibrio parahaemolyticus; auxiliary modules ... See more keywords
A Quorum Sensing-Regulated Type VI Secretion System Containing Multiple Nonredundant VgrG Proteins Is Required for Interbacterial Competition in Chromobacterium violaceum
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DOI: 10.1128/spectrum.01576-22
Abstract: The type VI secretion system (T6SS) is a contractile nanomachine used by many Gram-negative bacteria to inject toxic effectors into adjacent cells. The delivered effectors are bound to the components of a puncturing apparatus containing… read more here.
Keywords: system; competition; secretion; violaceum ... See more keywords