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   Articles with "t6ss" as a keyword



Burkholderia cenocepacia utilizes a type VI secretion system for bacterial competition

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recommendations! Published in 2019 at "MicrobiologyOpen"

DOI: 10.1002/mbo3.774

Abstract: Burkholderia cenocepacia is an opportunistic bacterial pathogen that poses a significant threat to individuals with cystic fibrosis by provoking a strong inflammatory response within the lung. It possesses a type VI secretion system (T6SS), a… read more here.

Keywords: cenocepacia; system; burkholderia cenocepacia; t6ss ... See more keywords

Hcp2b of T6SS affects colonization of avian pathogenic Escherichia coli and host keratin filament expression

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recommendations! Published in 2022 at "Avian Pathology"

DOI: 10.1080/03079457.2022.2031881

Abstract: ABSTRACT T6SS (type VI secretion system) is a type of nano-syringe that exists in APEC (avian pathogenic Escherichia coli). Hcp (haemolysin-coregulated protein) of T6SS participates in the regulation of virulence during APEC infection. However, whether… read more here.

Keywords: colonization; avian pathogenic; hcp2b; expression ... See more keywords

RpoN/Sfa2-dependent activation of the Pseudomonas aeruginosa H2-T6SS and its cognate arsenal of antibacterial toxins

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recommendations! Published in 2021 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkab1254

Abstract: Abstract Pseudomonas aeruginosa uses three type six secretion systems (H1-, H2- and H3-T6SS) to manipulate its environment, subvert host cells and for microbial competition. These T6SS machines are loaded with a variety of effectors/toxins, many… read more here.

Keywords: dependent activation; t6ss; pseudomonas aeruginosa; rpon sfa2 ... See more keywords

In silico investigation of the genus Campylobacter type VI secretion system reveals genetic diversity in organization and putative effectors

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recommendations! Published in 2022 at "Microbial Genomics"

DOI: 10.1099/mgen.0.000898

Abstract: Bacterial type VI secretion systems (T6SSs) are contractile nanomachines that deliver proteinic substrates into target prokaryotic or eukaryotic cells and the surrounding milieu. The genus Campylobacter encompasses 39 recognized species and 13 subspecies, with many… read more here.

Keywords: t6ss; type secretion; genus campylobacter; campylobacter ... See more keywords

Sporadic type VI secretion in seventh pandemic Vibrio cholerae.

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recommendations! Published in 2023 at "Microbiology"

DOI: 10.1099/mic.0.001329

Abstract: Vibrio cholerae is a pathogen that causes disease in millions of people every year by colonizing the small intestine and then secreting the potent cholera toxin. How the pathogen overcomes the colonization barrier created by… read more here.

Keywords: cholerae; vibrio cholerae; activity; type secretion ... See more keywords

The AraC‐type transcription factor TagK is a new player in the signaling cascade that induces the anti‐eukaryotic T6SS of Xanthomonas citri

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recommendations! Published in 2022 at "Molecular Microbiology"

DOI: 10.1111/mmi.14985

Abstract: Type 6 secretion systems (T6SSs) are specialized multiprotein complexes that inject protein effectors into prokaryotic and/or eukaryotic cells. We previously described the role of the T6SS of the phytopathogen Xanthomonas citri pv. citri as an… read more here.

Keywords: transcription; factor; citri; anti eukaryotic ... See more keywords

The accessory protein TagV is required for full Type VI secretion system activity in Serratia marcescens

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recommendations! Published in 2023 at "Molecular Microbiology"

DOI: 10.1111/mmi.15027

Abstract: The bacterial Type VI secretion system (T6SS) is a dynamic macromolecular structure that promotes inter‐ and intra‐species competition through the delivery of toxic effector proteins into neighbouring cells. The T6SS contains 14 well‐characterised core proteins… read more here.

Keywords: serratia marcescens; tagv; secretion system; activity ... See more keywords

Pseudomonas aeruginosa assembles H1-T6SS in response to physical and chemical damage of the outer membrane

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recommendations! Published in 2025 at "Science Advances"

DOI: 10.1126/sciadv.adr1713

Abstract: Bacteria respond to environmental stimuli and attacks from competing organisms. Pseudomonas aeruginosa assembles the type VI secretion system (H1-T6SS) to precisely retaliate against aggressive competing bacteria. However, we lack an understanding of how the H1-T6SS… read more here.

Keywords: outer membrane; t6ss response; t6ss; pseudomonas aeruginosa ... See more keywords

Soil Inoculation and Blocker-Mediated Sequencing Show Effects of the Antibacterial T6SS on Agrobacterial Tumorigenesis and Gallobiome

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recommendations! Published in 2023 at "mBio"

DOI: 10.1128/mbio.00177-23

Abstract: The T6SS is widespread among proteobacteria and used for interbacterial competition by agrobacteria, which are soil inhabitants and opportunistic bacterial pathogens causing crown gall disease in a wide range of plants. Current evidence indicates that… read more here.

Keywords: disease; inoculation; competition; soil inoculation ... See more keywords

Atomic Structure of IglD Demonstrates Its Role as a Component of the Baseplate Complex of the Francisella Type VI Secretion System

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recommendations! Published in 2022 at "mBio"

DOI: 10.1128/mbio.01277-22

Abstract: Francisella tularensis is a facultatively intracellular Gram-negative bacterium that causes the serious and potentially fatal zoonotic illness, tularemia. Because of its extraordinarily high infectivity and mortality to humans, especially when inhaled, F. tularensis is considered… read more here.

Keywords: francisella; structure; igld; baseplate ... See more keywords

A combination of genomics and transcriptomics provides insights into the distribution and differential mRNA expression of type VI secretion system in clinical Klebsiella pneumoniae

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recommendations! Published in 2024 at "mSphere"

DOI: 10.1128/msphere.00822-23

Abstract: ABSTRACT The type VI secretion system (T6SS) serves as a crucial molecular weapon in interbacterial competition and significantly influences the adaptability of bacteria in their ecological niche. However, the distribution and function of T6SS in… read more here.

Keywords: secretion system; type secretion; pneumoniae; t6ss ... See more keywords