Spike substitution T813S increases Sarbecovirus fusogenicity by enhancing the usage of TMPRSS2
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DOI: 10.1371/journal.ppat.1011123
Abstract: SARS-CoV Spike (S) protein shares considerable homology with SARS-CoV-2 S, especially in the conserved S2 subunit (S2). S protein mediates coronavirus receptor binding and membrane fusion, and the latter activity can greatly influence coronavirus infection.… read more here.
Keywords: fusogenicity; substitution; spike; t813s ... See more keywords