Selenium nanoparticles and quercetin suppress thioacetamide‐induced hepatocellular carcinoma in rats: Attenuation of inflammation involvement
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22989
Abstract: The current study investigates the anti‐inflammatory and hepatoprotective effects of selenium (Se) formulated as nanoparticles (SeNPs) and in combination with quercetin (QCT) against thioacetamide (TAA)‐induced hepatocellular carcinoma (HCC) in rats. Seventy‐two male Sprague–Dawley rats were… read more here.
Keywords: hepatocellular carcinoma; hcc; induced hepatocellular; taa ... See more keywords
Lessons from the NIST micronutrients quality assurance program for vitamin C, 1993 to 2015: sample stability, assay reproducibility, and use of controls to improve comparability
Sign Up to like & getrecommendations! Published in 2020 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-020-03021-9
Abstract: Vitamin C is a necessary micronutrient that is involved in many biological processes. In preserved human plasma and serum, vitamin C is most meaningfully analyzed as total ascorbic acid (TAA). From 1993 through 2015, the… read more here.
Keywords: sample; reproducibility; comparability; taa ... See more keywords
Chlorogenic acid, quercetin, coenzyme Q10 and silymarin modulate Keap1-Nrf2/heme oxygenase-1 signaling in thioacetamide-induced acute liver toxicity.
Sign Up to like & getrecommendations! Published in 2021 at "Life sciences"
DOI: 10.1016/j.lfs.2021.119460
Abstract: BACKGROUND AND AIMS The normal functioning of Kelch-like ECH-associated protein-1 (Keap1)/nuclear factor erythroid 2-related factor 2 (Nrf2) complex is necessary for the cellular protection against oxidative stress. We investigated the effect of chlorogenic acid (CGA),… read more here.
Keywords: keap1 nrf2; q10 silymarin; liver; q10 ... See more keywords
Thioacetamide additive assisted crystallization of solution-processed perovskite films for high performance planar heterojunction solar cells
Sign Up to like & getrecommendations! Published in 2020 at "Solar Energy Materials and Solar Cells"
DOI: 10.1016/j.solmat.2020.110435
Abstract: Abstract High-quality perovskite films with uniform coverage and large grains are indispensable to enhance the performance of perovskite solar cells with high efficiency and stability. However, solution-processed perovskite films usually possess small grains associated with… read more here.
Keywords: solution processed; crystallization; performance; taa ... See more keywords
Redox-Active Covalent Organic Frameworks with Nickel-Bis(dithiolene) Units as Guiding Layers for High-Performance Lithium Metal Batteries.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c01996
Abstract: Combining the chemistry of metal-organic frameworks (MOFs) and covalent organic frameworks (COFs) can bring new opportunities for the design of advanced materials with enhanced tunability and functionality. Herein, we constructed two COFs based on Ni-bis(dithiolene)… read more here.
Keywords: covalent organic; organic frameworks; taa; bis dithiolene ... See more keywords
Intra-articular injection of triamcinolone acetonide releasing biomaterial microspheres inhibits pain and inflammation in an acute arthritis model
Sign Up to like & getrecommendations! Published in 2019 at "Drug Delivery"
DOI: 10.1080/10717544.2019.1568625
Abstract: Abstract Inflammation of the synovium and joint capsule is a main driver of pain in an osteoarthritic (OA) joint. Triamcinolone acetonide (TAA) is a classical corticosteroid that reduces synovitis and alleviates pain, albeit transiently. Biomaterial-based… read more here.
Keywords: taa loaded; inflammation; articular injection; taa ... See more keywords
Identification and prioritization of tumor associated antigens for immunotherapeutic and diagnostic capacity in epithelial ovarian cancer: A systematic literature review.
Sign Up to like & getrecommendations! Published in 2022 at "Carcinogenesis"
DOI: 10.1093/carcin/bgac084
Abstract: Epithelial ovarian cancer (EOC) is a prevalent carcinoma in the female population associated with poor prognostic outcomes, in part due to the late stage of disease at diagnoses. Aiming to identify tumor associated antigens (TAAs)… read more here.
Keywords: epithelial ovarian; ovarian cancer; expression; taa ... See more keywords
Protective effect of cilostazol and verapamil against thioacetamide-induced hepatotoxicity in rats may involve Nrf2/GSK-3β/NF-κB signaling pathway.
Sign Up to like & getrecommendations! Published in 2022 at "Toxicology research"
DOI: 10.1093/toxres/tfac045
Abstract: Background Verapamil (VER) and cilostazol (Cilo) are mostly used as cardiovascular drugs; they have beneficial effects on different organs toxicities. Aim we investigated whether the Nuclear factor erythroid 2-related factor 2 (Nrf2), Glycogen synthase kinase-3β… read more here.
Keywords: verapamil; cilostazol; hepatotoxicity; taa ... See more keywords
Aging Alters the Aortic Proteome in Health and Thoracic Aortic Aneurysm
Sign Up to like & getrecommendations! Published in 2022 at "Arteriosclerosis, Thrombosis, and Vascular Biology"
DOI: 10.1161/atvbaha.122.317643
Abstract: Background: Aging enhances most chronic diseases but its impact on human aortic tissue in health and in thoracic aortic aneurysms (TAA) remains unclear. Methods: We employed a human aortic biorepository of healthy specimens (n=17) and… read more here.
Keywords: health; thoracic aortic; health thoracic; age ... See more keywords
Dissecting aortic aneurysm in Marfan syndrome is associated with losartan-sensitive transcriptomic modulation of aortic cells.
Sign Up to like & getrecommendations! Published in 2023 at "JCI insight"
DOI: 10.1172/jci.insight.168793
Abstract: To improve our limited understanding of the pathogenesis of thoracic aortic aneurysm (TAA) leading to acute aortic dissection, single-cell RNA sequencing (scRNA-seq) was employed to profile disease-relevant transcriptomic changes of aortic cell populations in a… read more here.
Keywords: cell; marfan syndrome; taa; aortic aneurysm ... See more keywords
Novel variants in the ACTA2 and MYH11 genes in a Cypriot family with thoracic aortic aneurysms: a case report
Sign Up to like & getrecommendations! Published in 2018 at "BMC Medical Genetics"
DOI: 10.1186/s12881-018-0728-0
Abstract: BackgroundThoracic aortic aneurysm (TAA) and/or thoracic aortic aneurysm and dissection (TAAD) is characterized by a considerable risk of morbidity and mortality of affected individuals. It is inherited in an autosomal dominant pattern and the 20%… read more here.
Keywords: cypriot family; family; case; report ... See more keywords