Articles with "taar1 agonist" as a keyword



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Review of the Trace Amine-Associated Receptor 1 (TAAR1) Agonist Ulotaront: Part II—Summary of Initial Clinical Efficacy/Safety Results

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Published in 2023 at "CNS Spectrums"

DOI: 10.1017/s1092852923001372

Abstract: Abstract Introduction Ulotaront is a trace amine-associated receptor 1 (TAAR1) agonist with serotonin 5-HT1A agonist activity that has received FDA Breakthrough Therapy Designation for the treatment of schizophrenia. Here we summarize ongoing clinical research characterizing… read more here.

Keywords: safety; efficacy; trace amine; taar1 agonist ... See more keywords
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Review of the TAAR1 Agonist Ulotaront: Part I—From Discovery to Clinic

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Published in 2023 at "CNS Spectrums"

DOI: 10.1017/s1092852923001384

Abstract: Abstract Introduction Trace amine-associated receptors (TAARs) are a family of G-protein-coupled receptors (GPCRs) first identified in 2001. TAAR1 has emerged as a promising therapeutic target due to its ability to modulate monoaminergic and glutamatergic neurotransmission.… read more here.

Keywords: pharmacology; trace amine; taar1 agonist; discovery ... See more keywords