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Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.1480
Abstract: This nonrandomized controlled trial investigates whether self-administered screening via an in-office tablet app was associated with improved detection of patients at risk for depression, injurious falls, or intimate partner violence compared with screening performed by…
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Keywords:
screening primary;
care practices;
tablet;
self administered ... See more keywords
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Published in 2021 at "Anatomical sciences education"
DOI: 10.1002/ase.2131
Abstract: The affordances of technology-based assessments, like the Objectively Structured Practical Examination, have become an integral part of gross anatomy courses. The Department of Anatomy Faculty of Medicine at the University of Warmia and Mazury developed…
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Keywords:
examination;
practical examination;
anatomy;
method ... See more keywords
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1
Published in 2022 at "Clinical pharmacology in drug development"
DOI: 10.1002/cpdd.1051
Abstract: GSK3640254 is a next-generation maturation inhibitor with demonstrated potency across HIV-1 subtypes and a high barrier to emergent resistance. This phase I, 2-part, randomized, open-label study (ClinicalTrials.gov identifier, NCT04263142) in healthy participants assessed the relative…
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Keywords:
food;
gsk3640254;
healthy participants;
part ... See more keywords
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Published in 2022 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.1087
Abstract: We assessed the bioequivalence of a single dose of 5‐mg of esaxerenone administered as an orally disintegrating tablet (ODT) with the conventional oral tablet in healthy Japanese men. This single‐center, open‐label, randomized, two‐drug, two‐stage crossover,…
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Keywords:
single dose;
orally disintegrating;
tablet;
disintegrating tablet ... See more keywords
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Published in 2022 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.1096
Abstract: This study aimed to evaluate the bioequivalence of two pazopanib tablet formulations in healthy Chinese subjects. A randomized, open‐label, single‐dose, two‐period, two‐sequence, crossover study was conducted under fasting conditions. A total of 32 eligible subjects…
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Keywords:
pazopanib tablet;
chinese subjects;
tablet;
generic branded ... See more keywords
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2
Published in 2022 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.1169
Abstract: Oral pharmacotherapy for overactive bladder, a condition that increases with age, includes anticholinergics and β3‐adrenergic receptor agonists. Older adults, including those with dysphagia, may have difficulty swallowing tablets. In this phase 1 study in healthy…
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Keywords:
vibegron;
pharmacokinetics safety;
tablet;
healthy adults ... See more keywords
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Published in 2023 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.1233
Abstract: Levothyroxine (LT4) is the standard of care for treating hypothyroidism. Despite the established efficacy of LT4, 50% of treated patients fail to achieve normal thyrotropin levels. Oral formulations of LT4 that bypass the gastric phase…
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Keywords:
bioavailability novel;
tablet;
concentration;
levothyroxine ... See more keywords
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Published in 2019 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.601
Abstract: The objective of this study was to evaluate the relative bioavailability of olanzapine in 3 olanzapine‐containing tablet formulations. ALKS 3831 is a fixed‐dose combination of olanzapine (OLZ, an atypical antipsychotic) and samidorphan (SAM, a μ‐opioid…
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Keywords:
bioequivalence;
alks 3831;
olz;
olanzapine ... See more keywords
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Published in 2021 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.938
Abstract: Semaglutide, a glucagon‐like peptide‐1 (GLP‐1) analogue, has been coformulated in a tablet with the absorption enhancer, sodium N‐(8‐[2‐hydroxybenzoyl] amino) caprylate (SNAC). We investigated tablet erosion and the pharmacokinetics of oral semaglutide administered with 2 different…
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Keywords:
water;
oral semaglutide;
tablet erosion;
tablet ... See more keywords
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Published in 2021 at "Clinical pharmacology in drug development"
DOI: 10.1002/cpdd.964
Abstract: A newly developed branded generic of a moxifloxacin (MOX) 400-mg tablet formulation was manufactured prior to this study. A bioequivalence (BE) study was done to assess the pharmacokinetics of the formulation using a randomized, open-label,…
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Keywords:
branded generic;
formulation;
generic moxifloxacin;
bioequivalence study ... See more keywords
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Published in 2018 at "Medical Physics"
DOI: 10.1002/mp.12786
Abstract: PURPOSE Our aim was to develop a portable quality control (QC) application using a thermometer, a barometer, an angle gauge, and a range finder implemented in a tablet-type consumer electronic device (CED) and to assess…
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Keywords:
angle;
application;
portable quality;
quality control ... See more keywords