Chiral Method by Normal Phase HPLC–UV for Quantitation of Lumefantrine Enantiomers in Tablet Formulations
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DOI: 10.1007/s10337-019-03811-z
Abstract: Evaluating lumefantrine enantioselectivity and properly quantifying its enantiomers is essential for a deeper understanding of the impact of the enantioselectivity in the pharmacodynamic and pharmacokinetic properties of the drug. For this, a chiral chromatographic method… read more here.
Keywords: phase; enantiomers tablet; lumefantrine; method ... See more keywords
A Facile and Novel Approach to Manufacture Paclitaxel-Loaded Proliposome Tablet Formulations of Micro or Nano Vesicles for Nebulization
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DOI: 10.1007/s11095-020-02840-w
Abstract: Purpose The aim of this study was to develop novel paclitaxel-loaded proliposome tablet formulations for pulmonary drug delivery. Method Proliposome powder formulations (i.e. F1 – F27) were prepared employing Lactose monohydrate (LMH), Microcrystalline cellulose (MCC)… read more here.
Keywords: nebulization; tablet formulations; paclitaxel loaded; proliposome tablet ... See more keywords
In Vitro Comparative Quality Evaluation of Non-Expired and 10 Years-Expired Lamotrigine Immediate-Release Tablet Formulations - Pilot Study
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DOI: 10.14227/dt270120p14
Abstract: This study aimed to compare the different physical parameters and dissolution profiles of 10 years-expired with nonexpired lamotrigine (LTG) immediate-release tablet formulations. Dissolution tests were conducted using a validated high-performance liquid chromatography method. Dissolution characteristics… read more here.
Keywords: years expired; immediate release; tablet formulations; release tablet ... See more keywords
Bioequivalence of two tablet formulations of cefpodoxime proxetil in beagle dogs
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2022.1048823
Abstract: The pharmacokinetic profiles and bioequivalence of two cefpodoxime proxetil tablets were investigated in Beagle dogs. A single-dose, four-way complete replication and crossover design was used in the present study. A total of 28 healthy Beagle… read more here.
Keywords: cefpodoxime proxetil; bioequivalence two; bioequivalence; beagle dogs ... See more keywords
A Novel Validated UHPLC Method for the Estimation of Rosuvastatin and Its Complete Impurity Profile in Tablet Formulations
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DOI: 10.3390/molecules28010431
Abstract: A key step in the development of medicinal products is the research and validation of selective and sensitive analytical methods for the control of impurities from synthesis and degradation. As most impurities are similar in… read more here.
Keywords: novel validated; validated uhplc; uhplc method; rsv ... See more keywords
Development of Robust Tablet Formulations with Enhanced Drug Dissolution Profiles from Centrifugally-Spun Micro-Fibrous Solid Dispersions of Itraconazole, a BCS Class II Drug
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DOI: 10.3390/pharmaceutics15030802
Abstract: Fibre-based oral drug delivery systems are an attractive approach to addressing low drug solubility, although clear strategies for incorporating such systems into viable dosage forms have not yet been demonstrated. The present study extends our… read more here.
Keywords: tablet formulations; dissolution; drug; bcs class ... See more keywords
A Directly Compressible Pregelatinised Sago Starch: A New Excipient in the Pharmaceutical Tablet Formulations
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DOI: 10.3390/polym14153050
Abstract: An excipient intended for direct compression in pharmaceutical tableting must show important features of flowability and compactibility. This study investigated pregelatinised sago starch as an excipient for direct compression tablets. Pregelatinised sago starch was prepared… read more here.
Keywords: tablet formulations; sago starch; directly compressible; pregelatinised sago ... See more keywords
Evaluation of two different orally disintegrating tablet formulations containing flurbiprofen inclusion complex and its solid dispersion
Sign Up to like & getrecommendations! Published in 2023 at "Tropical Journal of Pharmaceutical Research"
DOI: 10.4314/tjpr.v22i4.1
Abstract: Purpose: To prepare orally dispersible tablet formulations (ODTs) by increasing the solubility of flurbiprofen (FB), which has low water solubility. Methods: The ODTs were prepared using direct compression method the inclusion complexes and solid dispersions… read more here.
Keywords: solid dispersions; inclusion complex; solubility; containing flurbiprofen ... See more keywords