Systematic study of paracetamol powder mixtures and granules tabletability: key role of rheological properties and dynamic image analysis.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2021.121110
Abstract: The aim of this systematic study was to analyze the granulometric and rheological behavior of tableting mixtures in relation to tabletability by single tablet and lab-scale batch compression with an eccentric tablet machine. Three mixtures… read more here.
Keywords: compression; tabletability; powder; lab scale ... See more keywords
Aggregate Elasticity and Tabletability of Molecular Solids: a Validation and Application of Powder Brillouin Light Scattering
Sign Up to like & getrecommendations! Published in 2018 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-018-1194-x
Abstract: Describing the elastic deformation of single-crystal molecular solids under stress requires a comprehensive determination of the fourth-rank stiffness tensor (Cijkl). Single crystals are, however, rarely utilized in industrial applications, and thus averaging techniques (e.g., the… read more here.
Keywords: powder brillouin; moduli; tabletability; brillouin light ... See more keywords
Using a Material Library to Understand the Change of Tabletability by High Shear Wet Granulation
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14122631
Abstract: Understanding the tabletability change of materials after granulation is critical for the formulation and process design in tablet development. In this paper, a material library consisting of 30 pharmaceutical materials was used to summarize the… read more here.
Keywords: high shear; change tabletability; change; tabletability ... See more keywords