Articles with "tac01 cldn18" as a keyword



Abstract CT081: A phase 1/2 study investigating the safety and efficacy of autologous TAC T cells in subjects with unresectable, locally advanced, or metastatic claudin 18.2+ solid tumors

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Published in 2024 at "Cancer Research"

DOI: 10.1158/1538-7445.am2024-ct081

Abstract: Background: CLDN18.2 is a tight junction protein found in differentiated gastric epithelial cells, which can become abnormally or ectopically expressed in a number of solid tumor indications. This exposure profile illustrates the potential of CLDN18.2… read more here.

Keywords: cldn18; tac01 cldn18; tac; efficacy ... See more keywords