Diffuse gliomas with FGFR3‐TACC3 fusion have characteristic histopathological and molecular features
Sign Up to like & getrecommendations! Published in 2018 at "Brain Pathology"
DOI: 10.1111/bpa.12563
Abstract: Adult glioblastomas, IDH‐wildtype represent a heterogeneous group of diseases. They are resistant to conventional treatment by concomitant radiochemotherapy and carry a dismal prognosis. The discovery of oncogenic gene fusions in these tumors has led to… read more here.
Keywords: fgfr3 tacc3; tacc3 fusion; diffuse gliomas; molecular features ... See more keywords
Varied histomorphology and clinical outcomes of FGFR3-TACC3 fusion gliomas.
Sign Up to like & getrecommendations! Published in 2022 at "Neurosurgical focus"
DOI: 10.3171/2022.9.focus22420
Abstract: Targeted therapies for driver gene fusions in cancers have yielded substantial improvements in care. Here, the authors outline a case series of 6 patients with FGFR3-TACC3 fusion in primary brain tumors ranging from polymorphous low-grade… read more here.
Keywords: fusion; varied histomorphology; fgfr3 tacc3; histomorphology clinical ... See more keywords