Preclinical Development and Validation of Translational Temperature Sensitive Iodized Oil Emulsion Mediated Transcatheter Arterial Chemo-Immuno-Embolization for the Treatment of Hepatocellular Carcinoma.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300906
Abstract: Substantial research has been conducted on effective approaches for harnessing the antitumor potential of combination immunotherapies directed at the tumor. The synergistic enhancement of cancer therapeutic efficacy can be achieved through the combination of interventional… read more here.
Keywords: hepatocellular carcinoma; immuno embolization; arterial chemo; tace ... See more keywords
Arginine‐Loaded Nano‐Calcium‐Phosphate‐Stabilized Lipiodol Pickering Emulsions Potentiates Transarterial Embolization‐Immunotherapy
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DOI: 10.1002/advs.202410484
Abstract: Transarterial chemoembolization (TACE) continues to stand as a primary option for treating unresectable hepatocellular carcinoma (HCC). However, the increased tumor hypoxia and acidification will lead to the immunosuppressive tumor microenvironment (TME) featuring exhausted T cells,… read more here.
Keywords: emulsion; lipiodol pickering; tace; calcium phosphate ... See more keywords
Efficacy and safety of TACE combined with lenvatinib and PD-1 inhibitors for unresectable recurrent HCC: A multicenter, retrospective study.
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DOI: 10.1002/cam4.5880
Abstract: There is no consensus on the optimal regimen for unresectable recurrent hepatocellular carcinoma (HCC), so this retrospective study aimed to evaluate the efficacy and safety of transarterial chemoembolization (TACE) combined with lenvatinib and PD‐1 inhibitors… read more here.
Keywords: retrospective study; combined lenvatinib; tace; tace combined ... See more keywords
Testis‐specific isoform of angiotensin‐converting enzyme (tACE) is involved in the regulation of bovine sperm capacitation
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DOI: 10.1002/mrd.22790
Abstract: We hypothesized that the testis‐specific isoform of angiotensin‐converting enzyme (tACE) is released during bovine sperm capacitation, and its peptidase activity is required for capacitation. Specific objectives of this study were to (i) develop an anti‐tACE… read more here.
Keywords: bovine sperm; sperm capacitation; tace; specific isoform ... See more keywords
Mineralized Supramolecular Microspheres with Immunoregulating Functions for Transarterial Chemoembolization Immunotherapy of Hepatocellular Carcinoma.
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DOI: 10.1002/smtd.202500857
Abstract: Transcatheter arterial chemoembolization (TACE) is a pivotal therapeutic option for hepatocellular carcinoma (HCC) at intermediate or advanced stage. However, conventional TACE, which primarily relies on embolic microspheres for localized chemotherapy, suffers from limitations such as… read more here.
Keywords: tace; immunotherapy; transarterial chemoembolization; hepatocellular carcinoma ... See more keywords
Postoperative adjuvant transarterial chemoembolisation improves survival of hepatocellular carcinoma patients with microvascular invasion: A multicenter retrospective cohort
Sign Up to like & getrecommendations! Published in 2023 at "United European Gastroenterology Journal"
DOI: 10.1002/ueg2.12365
Abstract: Abstract Background We aimed to investigate the efficacy of postoperative adjuvant transarterial chemoembolisation (PA‐TACE) in patients with hepatocellular carcinoma (HCC) complicated by microvascular invasion (MVI). Methods A retrospective analysis of 1505 patients with HCC who… read more here.
Keywords: adjuvant transarterial; postoperative adjuvant; hepatocellular carcinoma; tace ... See more keywords
Role of preoperative transarterial chemoembolization (TACE) in intermediate‐stage hepatocellular carcinoma (Hong Kong liver cancer stage IIB)
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DOI: 10.1002/wjs.12420
Abstract: Abstract Introduction Transarterial chemoembolization (TACE) has an established role in advanced HCC. The present study evaluates the role of TACE as a neoadjuvant modality in the management of intermediate HCC [Hong Kong Liver Cancer (HKLC)… read more here.
Keywords: tace; role; intermediate stage; stage ... See more keywords
Interobserver variability in target volume delineation of hepatocellular carcinoma
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DOI: 10.1007/s00066-017-1177-y
Abstract: BackgroundDefinition of gross tumor volume (GTV) in hepatocellular carcinoma (HCC) requires dedicated imaging in multiple contrast medium phases. The aim of this study was to evaluate the interobserver agreement (IOA) in gross tumor delineation of… read more here.
Keywords: ioa; hcc; tace; war ... See more keywords
Computed tomographic perfusion with 160-mm coverage: comparative analysis of hepatocellular carcinoma treated by two transarterial chemoembolization courses relative to magnetic resonance imaging findings
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DOI: 10.1007/s00261-018-1714-x
Abstract: PurposeThe aim of this study was to assess hepatocellular carcinoma (HCC) response with CT perfusion parameters before and after two transarterial chemo embolization (TACE) courses compared with MRI, and to search for predictive factors of… read more here.
Keywords: hepatocellular carcinoma; tace; response; two transarterial ... See more keywords
Current status of the combination therapy of transarterial chemoembolization and local ablation for hepatocellular carcinoma
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DOI: 10.1007/s00261-019-01943-2
Abstract: Purpose of reviewTo review the current status and ideal time interval of the combination therapy of transarterial chemoembolization (TACE) and local ablation for patients with HCCs.Recent findingsIn recent years, local ablation has been proposed as… read more here.
Keywords: tace; ablation; current status; local ablation ... See more keywords
Validation of the Risk Prediction Models STATE-Score and START-Strategy to Guide TACE Treatment in Patients with Hepatocellular Carcinoma
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DOI: 10.1007/s00270-017-1606-4
Abstract: PurposeSeveral scoring systems that guide patients’ treatment regimen for transarterial chemoembolization (TACE) of hepatocellular carcinoma (HCC) have been introduced, but none have gained widespread acceptance in clinical practice. The purpose of this study is to… read more here.
Keywords: state; state score; tace; start strategy ... See more keywords