Soluble Sema4D cleaved from osteoclast precursors by TACE suppresses osteoblastogenesis.
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DOI: 10.1111/jcmm.17416
Abstract: Bone remodelling is mediated by orchestrated communication between osteoclasts and osteoblasts which, in part, is regulated by coupling and anti-coupling factors. Amongst formally known anti-coupling factors, Semaphorin 4D (Sema4D), produced by osteoclasts, plays a key… read more here.
Keywords: tace mab; tace; osteoclast precursors; anti tace ... See more keywords