In Vitro Study of Antitumor Effect of Antimicrobial Peptide Tachyplesin I in Combination with Cisplatin
Sign Up to like & getrecommendations! Published in 2018 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-018-4134-6
Abstract: We studied combined effect of β-hairpin antimicrobial peptide tachyplesin I and cytotoxic agent cisplatin on tumor and normal human cell lines. MTT assay and flow cytometry showed that tachyplesin I selectively sensitized cancer cells to… read more here.
Keywords: tachyplesin; cisplatin; peptide tachyplesin; effect ... See more keywords
Cyclic analogues of horseshoe crab peptide tachyplesin I with anticancer and cell penetrating properties.
Sign Up to like & getrecommendations! Published in 2019 at "ACS chemical biology"
DOI: 10.1021/acschembio.9b00782
Abstract: Tachyplesin-I (TI) is a host defense peptide from the horseshoe crab Tachypleus tridentatus that has outstanding potential as an anticancer therapeutic lead. Backbone cyclized TI (cTI) has similar anticancer properties to TI, but has higher… read more here.
Keywords: peptide; tachyplesin; horseshoe crab; cell penetrating ... See more keywords