Long-Term Tacrolimus Blood Trough Level and Patient Survival in Adult Liver Transplantation
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DOI: 10.3390/jpm11020090
Abstract: Tacrolimus is the most widely used immunosuppressant in liver transplant (LT) patients. However, the ideal long-term target level for these patients is unknown. This retrospective study aimed to investigate the impact of tacrolimus blood concentration… read more here.
Keywords: long term; tacrolimus blood; level;
Relationship between CYP3A5 Polymorphism and Tacrolimus Blood Concentration Changes in Allogeneic Hematopoietic Stem Cell Transplant Recipients during Continuous Infusion
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DOI: 10.3390/ph14040353
Abstract: A polymorphism in the gene encoding the metabolic enzyme cytochrome P450 family 3 subfamily A member 5 (CYP3A5) is a particularly influential factor in the use of tacrolimus in Japanese patients. Those who are homozygotic… read more here.
Keywords: cyp3a5 polymorphism; tacrolimus blood; blood; blood concentration ... See more keywords