CYP3A5 Genotype-Dependent Drug-Drug Interaction Between Tacrolimus and Nifedipine in Chinese Renal Transplant Patients
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DOI: 10.3389/fphar.2021.692922
Abstract: Purpose: The drug-drug interactions (DDIs) of tacrolimus greatly contributed to pharmacokinetic variability. Nifedipine, frequently prescribed for hypertension, is a competitive CYP3A5 inhibitor which can inhibit tacrolimus metabolism. The objective of this study was to investigate… read more here.
Keywords: transplant patients; cyp3a5 genotype; tacrolimus nifedipine; drug ... See more keywords