Patient-Focused Selection of PrEP Medication for Individuals at Risk of HIV: A Narrative Review
Sign Up to like & getrecommendations! Published in 2021 at "Infectious Diseases and Therapy"
DOI: 10.1007/s40121-020-00384-5
Abstract: Pre-exposure prophylaxis (PrEP) medication is a key component of the HIV prevention strategy in the US, which has been demonstrated to be highly effective in preventing HIV acquisition among individuals at risk. Two PrEP medications… read more here.
Keywords: risk hiv; prep medication; medication; taf ... See more keywords
Impact d’un traitement anti-fongique (TAF) préopératoire (pOP) dans la prise en charge des aspergilloses pulmonaires chroniques (APC) opérées – résultats d’une cohorte de 71 cas
Sign Up to like & getrecommendations! Published in 2017 at "Revue Des Maladies Respiratoires"
DOI: 10.1016/j.rmr.2016.10.232
Abstract: Introduction Bien que responsable d’une morbi-mortalite importante, la chirurgie est le seul traitement curatif de l’APC. L’administration d’un TAF perioperatoire bien que recommandee (niveau A) repose sur des recommandations de faible niveau de preuve (niveau… read more here.
Keywords: chez; cas; taf pop; taf ... See more keywords
Week 48 Resistance Analyses of the Once-Daily, Single-Tablet Regimen Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (D/C/F/TAF) in Adults Living with HIV-1 from the Phase III Randomized AMBER and EMERALD Trials
Sign Up to like & getrecommendations! Published in 2019 at "AIDS Research and Human Retroviruses"
DOI: 10.1089/aid.2019.0111
Abstract: Darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) 800/150/200/10 mg is being investigated in two Phase III trials, AMBER (NCT02431247; treatment-naive adults) and EMERALD (NCT02269917; treatment-experienced, virologically suppressed adults). Week 48 AMBER and EMERALD resistance analyses are presented. Postbaseline samples for… read more here.
Keywords: emtricitabine tenofovir; resistance; tenofovir; week ... See more keywords
Pharmacokinetics of Co-encapsulated Antiretrovirals with Ingestible Sensors.
Sign Up to like & getrecommendations! Published in 2019 at "AIDS research and human retroviruses"
DOI: 10.1089/aid.2019.0202
Abstract: We investigated the use of a system with an ingestible sensor (Proteus Digital Health Feedback system) co-encapsulated with antiretrovirals (ARVs) to measure real-time adherence. To assess the safety and impact, if any, co-encapsulation might have… read more here.
Keywords: encapsulated antiretrovirals; cmax; auc; ftc ... See more keywords
1041. Tenofovir alafenamide associated weight change in persons living with HIV
Sign Up to like & getrecommendations! Published in 2020 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofaa439.1227
Abstract: Persons living with human immunodeficiency virus (PLWH) have a higher incidence of developing obesity, diabetes, and cardiovascular disease. TAF, a newer formulation of tenofovir, has favorable effects on renal function and bone mineral density compared… read more here.
Keywords: tenofovir; change; persons living; taf ... See more keywords
Advanced HIV Infection in Treatment-Naïve Individuals: Effectiveness and Persistence of Recommended 3-Drug Regimens
Sign Up to like & getrecommendations! Published in 2022 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofac018
Abstract: Abstract Background Approximately 20% of newly diagnosed people with HIV (PWH) in the United States have advanced HIV infection, yet the literature on current antiretroviral therapy (ART) options is limited. The discontinuation/modification and effectiveness of… read more here.
Keywords: taf; advanced hiv; bdrv; drug ... See more keywords
The Use of Tenofovir Disoproxil Fumarate and Tenofovir Alafenamide for Preventing Vertical Transmission of Hepatitis B
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Gastroenterology"
DOI: 10.1097/mcg.0000000000001785
Abstract: Background: Mother-to-child transmission (MTCT) of hepatitis B virus may occur in highly viremic mothers despite the infants receiving appropriate immunoprophylaxis. We aimed to review tenofovir disoproxil fumarate (TDF) and tenofovir alafenamide (TAF) data for preventing… read more here.
Keywords: taf; tenofovir disoproxil; hepatitis; disoproxil fumarate ... See more keywords
Week 96 results of a phase 3 trial of darunavir/cobicistat/emtricitabine/tenofovir alafenamide in treatment-naïve HIV-1 patients.
Sign Up to like & getrecommendations! Published in 2019 at "AIDS"
DOI: 10.1097/qad.0000000000002463
Abstract: BACKGROUND Darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) 800/150/200/10mg was investigated through 96 weeks in AMBER (NCT02431247). METHODS Treatment-naïve, HIV-1-positive adults (screening plasma viral load [VL]≥1000 copies/ml; CD4 count >50 cells/mm) were randomized (1:1) to D/C/F/TAF (N=362) or D/C… read more here.
Keywords: week results; emtricitabine tenofovir; darunavir; tenofovir ... See more keywords
Response to Noe, Oldenbuettel and Jaeger
Sign Up to like & getrecommendations! Published in 2019 at "HIV Medicine"
DOI: 10.1111/hiv.12835
Abstract: Dear Sir, We thank Noe, Oldenbuettel and Jaeger for their interest in our article focusing on tenofovir alafenamide (TAF). They express concern that our article is “lacking a critical discussion about the increasing evidence of… read more here.
Keywords: medicine; gain; study; taf ... See more keywords
Overexpression of FOXD2-AS1 enhances proliferation and impairs differentiation of glioma stem cells by activating the NOTCH pathway via TAF-1.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of cellular and molecular medicine"
DOI: 10.1111/jcmm.17268
Abstract: Emerging data have highlighted the importance of long noncoding RNAs (lncRNAs) in exerting critical biological functions and roles in different forms of brain cancer, including gliomas. In this study, we sought to investigate the role… read more here.
Keywords: glioma; foxd2 as1; taf; lncrna foxd2 ... See more keywords
P074 Significant efficacy and long term safety difference with taf-based str in naïve adults
Sign Up to like & getrecommendations! Published in 2017 at "Sexually Transmitted Infections"
DOI: 10.1136/sextrans-2017-053232.119
Abstract: Introduction At Week(W) 48, elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (E/C/F/TAF) was statistically noninferior to E/C/F/tenofovir disoproxil fumarate(TDF) for the proportion of subjects with HIV-1 RNA read more here.
Keywords: participants taf; p074 significant; renal safety; safety ... See more keywords