ADRENAL und die Kontroverse zu Hydrokortison im septischen Schock
Sign Up to like & getrecommendations! Published in 2018 at "Medizinische Klinik - Intensivmedizin und Notfallmedizin"
DOI: 10.1007/s00063-018-0410-5
Abstract: Ergebnisse. Über einen Zeitraum von 4 Jahren wurden 3800 Patienten randomisiert. Der Endpunkt der 90-TageSterblichkeit konnte für 3658 Patienten erfasst werden. 511 Patienten (27,9%) der Hydrokortisongruppe und 526 Patienten (28,8%) der Placebogruppe waren am Tag… read more here.
Keywords: der hydrokortisongruppe; der; tage; patienten der ... See more keywords
Synergistic Effect of Tangeretin and Atorvastatin for Colon Cancer Combination Therapy: Targeted Delivery of These Dual Drugs Using RGD Peptide Decorated Nanocarriers
Sign Up to like & getrecommendations! Published in 2020 at "Drug Design, Development and Therapy"
DOI: 10.2147/dddt.s256636
Abstract: Purpose Colorectal cancer (CRC) is the third most frequently diagnosed cancer and the fourth leading cause of cancer death over the world. Nano-sized drug delivery systems are used for the treatment of cancers. The aim… read more here.
Keywords: tage; rgd; cancer; colon cancer ... See more keywords
Intracellular Toxic Advanced Glycation End-Products May Induce Cell Death and Suppress Cardiac Fibroblasts
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DOI: 10.3390/metabo12070615
Abstract: Cardiovascular disease (CVD) is a lifestyle-related disease (LSRD) induced by the dysfunction and cell death of cardiomyocytes. Cardiac fibroblasts are activated and differentiate in response to specific signals, such as transforming growth factor-β released from… read more here.
Keywords: cell death; cardiac fibroblasts; death; advanced glycation ... See more keywords
Potential of an Interorgan Network Mediated by Toxic Advanced Glycation End-Products in a Rat Model
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DOI: 10.3390/nu13010080
Abstract: Excessive intake of glucose and fructose in beverages and foods containing high-fructose corn syrup (HFCS) plays a significant role in the progression of lifestyle-related diseases (LSRD). Glyceraldehyde-derived advanced glycation end-products (AGEs), which have been designated… read more here.
Keywords: gene expression; end products; glycation end; tage ... See more keywords
Intracellular Toxic Advanced Glycation End-Products in 1.4E7 Cell Line Induce Death with Reduction of Microtubule-Associated Protein 1 Light Chain 3 and p62
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DOI: 10.3390/nu14020332
Abstract: Background: The death of pancreatic islet β-cells (β-cells), which are the insulin-producing cells, promote the pathology in both Type 1 and Type 2 diabetes mellitus (DM) (T1DM and T2DM), and they are protected by autophagy… read more here.
Keywords: cell; end products; death; glycation end ... See more keywords
The Association between Accumulation of Toxic Advanced Glycation End-Products and Cytotoxic Effect in MC3T3-E1 Cells
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DOI: 10.3390/nu14050990
Abstract: In diabetic patients, the metabolism of excess glucose increases the toxicity of the aldehyde group of sugar. Aldehydes, including glyceraldehyde (GA), react with intracellular proteins to form advanced glycation end-products (AGEs), which deteriorate bone quality… read more here.
Keywords: end products; accumulation; glycation end; advanced glycation ... See more keywords