Microglia mediate neurocognitive deficits by eliminating C1q-tagged synapses in sepsis-associated encephalopathy
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DOI: 10.1126/sciadv.abq7806
Abstract: Sepsis-associated encephalopathy (SAE) is a severe and frequent complication of sepsis causing delirium, coma, and long-term cognitive dysfunction. We identified microglia and C1q complement activation in hippocampal autopsy tissue of patients with sepsis and increased… read more here.
Keywords: sepsis; associated encephalopathy; tagged synapses; sepsis associated ... See more keywords