Simultaneous Tagmentation-Based Detection of ChIP/ATAC Signal with Bisulfite Sequencing.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1597-3_19
Abstract: DNA methylation is thought to regulate accessibility of chromatin and binding of regulatory elements; however, it is difficult to determine if chromatin accessibility or transcription factor (TF) binding overlap with methylated or unmethylated DNA if… read more here.
Keywords: detection chip; accessibility; based detection; simultaneous tagmentation ... See more keywords
Tagmentation-based single-cell genomics.
Sign Up to like & getrecommendations! Published in 2021 at "Genome research"
DOI: 10.1101/gr.275223.121
Abstract: It has been just over 10 years since the initial description of transposase-based methods to prepare high-throughput sequencing libraries, or "tagmentation," in which a hyperactive transposase is used to simultaneously fragment target DNA and append… read more here.
Keywords: single cell; tagmentation; cell genomics; based single ... See more keywords