Cystatin B-deficiency triggers ectopic histone H3 tail cleavage during neurogenesis
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DOI: 10.1016/j.nbd.2021.105418
Abstract: Cystatin B (CSTB) acts as an inhibitor of cysteine proteases of the cathepsin family and loss-of-function mutations result in human brain diseases with a genotype-phenotype correlation. In the most severe case, CSTB-deficiency disrupts brain development,… read more here.
Keywords: histone tail; cleavage; cystatin; tail cleavage ... See more keywords